Ann Dermatol.  2018 Oct;30(5):610-613. 10.5021/ad.2018.30.5.610.

Acquired Partial Lipodystrophy (Barraquer-Simons Syndrome): Early Cosmetic Intervention with Autologous Fat

• Rho NK
• Kim WS

• KMID: 2419755
• DOI: http://doi.org/10.5021/ad.2018.30.5.610

Abstract

Barraquer-Simons syndrome is a rare acquired lipodystrophy characterized by gradually symmetric subcutaneous fat loss in a craniocaudal distribution, often associated with hypocomplementemia and nephropathies. Facial cosmetic treatment in this disorder has not been fully described in the literature. We present a patient with Barraquer-Simons syndrome with emphasis on early cosmetic intervention with autologous fat grafting and its long-term efficacy. At the follow-up 37 months after the last fat grafting, preservation of the grafted fat was noted while lipodystrophy progressed in the trunk regions. Autologous fat grafting is suggested for the correction of facial dysmorphism in this type of lipodystrophy.

Keyword

Autografts; Lipectomy; Lipodystrophy; Subcutaneous fat

MeSH Terms

Autografts
Follow-Up Studies
Humans
Lipectomy
Lipodystrophy*
Subcutaneous Fat
Transplants

Figure

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  Fig. 1 (A) Markedly decreased subcutaneous fat in the abdomen, which accentuates the contour of muscles. (B) Fat depositions in the gluteal and thigh regions.

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  Fig. 2 (A) A preoperative photograph of the face demonstrating a significant fat loss mainly on cheeks, creating an old and wasted look. (B) A follow-up photograph 3.7 years after three fat grafting sessions showing stable results in the mid- and lower face injections.

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  Fig. 3 Computed tomography images of the abdomen and pelvis demonstrate a fat distribution characteristic of acquired partial lipodystrophy (Barraquer-Simons syndrome). Near complete absence of subcutaneous fat in the abdomen (A), in contrast to the prominence of gluteal fat at the level of the pelvis (B).

Reference

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