Clin Mol Hepatol.
2018 Jun;24(2):163-168. 10.3350/cmh.2017.0002.
Living-donor liver transplantation for giant hepatic hemangioma with diffuse hemangiomatosis in an adult: a case report
- Affiliations
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- 1Department of Internal Medicine, Seoul National University Bundang Hospital, College of Medicine, Seoul National University, Seongnam, Korea. jsh@snubh.org
- 2Department of Radiology, Seoul National University Bundang Hospital, College of Medicine, Seoul National University, Seongnam, Korea.
- 3Department of Surgery, Seoul National University Bundang Hospital, College of Medicine, Seoul National University, Seongnam, Korea.
- 4Department of Pathology, Seoul National University Bundang Hospital, College of Medicine, Seoul National University, Seongnam, Korea.
- KMID: 2417063
- DOI: http://doi.org/10.3350/cmh.2017.0002
Abstract
- Hepatic hemangioma represents the most common benign primary hepatic neoplasm. Although most such tumors are small and asymptomatic, giant hepatic hemangioma is frequently symptomatic, and requires intervention. Moreover, diffuse multiple hepatic hemangiomatosis occupying almost the entire liver is extremely rare in adults, and the optimal management for this condition is unclear. We report a case of a rapidly growing, symptomatic giant hepatic hemangioma with diffuse hepatic hemangiomatosis in a 50-year-old female patient who was treated by living-donor liver transplantation. This case shows malignant behavior of a benign hemangioma that required liver transplantation. Although this case could not meet the criteria for transplantation according to the MELD (model for end-stage liver disease) score system, it should be considered as an exceptional indication for deceased-donor liver allocation. Further studies of the mechanism underlying hemangioma growth are warranted.
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