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Biliary cystadenoma in an endemic zone of hydatid cyst: A rare surgical surprise

Ramavath K, Kaman L, Gupta A, Singh A, Das A

The advancement of radiological investigations has led to the early and incidental detection of hepatic cystic lesions. These are most commonly the simple cysts but can be malignant as well....
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Analysis of Prognosis according to Type of Health Insurance in Five Major Gastrointestinal Cancer Patients in Public Hospitals: Single-institution Retrospective Study

Lee DS, Lee J, Kim JW, Lee KL, Kim BG, Kim SH, Jung YJ

BACKGROUND/AIMS: Public hospitals were established to provide high quality medical services to low socioeconomic status patients. This study examined the effects of public hospitals on the treatment and prognosis of...
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Long-term Disease-free Survival after Trimodality Treatment of Recurrent Hepatocellular Carcinoma Involving the Inferior Vena Cava and Right Atrium

Park S, Yoon WS, Yim HJ, Rim CH

Hepatocellular carcinoma (HCC) involving the inferior vena cava (IVC) and/or right atrium (RA) is a rare and intractable disease. A standard treatment has not been established yet, owing to the...
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Malignant Hepatic Solitary Fibrous Tumor

Kim HI, In SK, Yi HS, Lee MJ, Kim HY

Hepatic solitary fibrous tumors (SFTs) are mostly benign and rare because of information regarding the clinical symptoms, treatment, and prognosis of their malignant forms is currently lacking. A literature review...
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Tenofovir and Entecavir Have Similar Renal Adverse Events on Hepatocellular Carcinoma Patients Treated with Transarterial Chemoembolization

Cho YY, Choi YH, Yu SJ, Cho EJ, Lee JH, Kim YJ, Yoon JH

BACKGROUND/AIMS: Tenofovir disoproxil fumarate (TDF) is potentially nephrotoxic in chronic hepatitis B patients. Hepatocellular carcinoma (HCC) patients treated using transarterial chemoembolization (TACE) are at an increased risk of renal injury....
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Underlying liver disease and advanced stage liver cancer are associated with elevated neutrophil-lymphocyte ratio

Wong L, Bozhilov K, Hernandez , Kwee S, Chan O, Ellis L, LeMarchand L

BACKGROUND/AIMS: Inflammation-based scores, such as the neutrophil-to-lymphocyte ratio (NLR), have been associated with prognosis in hepatocellular carcinoma (HCC); but variable cut-off values and potential lack of specificity have limited the...
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Hepatocellular carcinoma surveillance in the 21st century: Saving lives or causing harm?

Hanouneh I, Alkhouri N, Singal AG

Hepatocellular carcinoma (HCC) is the third most common cause of cancer related death worldwide. Prognosis and treatment options largely depend on tumor stage at diagnosis, with curative treatments only available...
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Comparison of international guidelines for noninvasive diagnosis of hepatocellular carcinoma: 2018 update

Kim TH, Kim SY, Tang A, Lee JM

The goal of this review is to present the similarities and differences among the latest guidelines for noninvasive diagnosis of hepatocellular carcinoma (HCC) of American Association for the Study of...
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Gadoxetic acid-enhanced magnetic resonance imaging: Hepatocellular carcinoma and mimickers

Kim YY, Park MS, Aljoqiman , Choi JY, Kim MJ

Gadoxetic acid, a hepatocyte-specific magnetic resonance imaging (MRI) contrast agent, has emerged as an important tool for hepatocellular carcinoma (HCC) diagnosis. Gadoxetic acid-enhanced MRI is useful for the evaluation of...
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A Proposal for Modification of the Barcelona Clinic Liver Cancer Staging System Considering the Prognostic Implication of Performance Status

Cho HJ, Kim SS, Kang SY, Yang MJ, Noh CK, Hwang JC, Lim SG, Shin SJ, Lee KM, Yoo BM, Lee KJ, Kim JH, Cho SW, Cheong JY, on behalf of the Korean Liver Cancer Association

BACKGROUND/AIMS: Barcelona Clinic Liver Cancer (BCLC) C stage demonstrates considerable heterogeneity because it includes patients with either symptomatic tumors (performance status [PS], 1–2) or with an invasive tumoral pattern reflected...
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The Occurrence and Risk Assessment of Exposure to Aflatoxin M₁ in Ultra-High Temperature and Pasteurized Milk in Hamadan Province of Iran

Nejad AS, Heshmati A, Ghiasvand

OBJECTIVES: Aflatoxins are a category of poisonous compounds found in most plants, milk and dairy products. The present research was carried out to detect the presence of aflatoxin M₁ (AFM₁)...
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2018 Korean Liver Cancer Association and National Cancer Center for Clinical Practice Guidelines of Hepatocellular Carcinoma: What's Different from 2014?

Kim JH

The Korean clinical practice guidelines for the management of hepatocellular carcinoma (HCC) was originally enacted in 2004 by the Korean Liver Cancer Association (KLCA)-National Cancer Center (NCC) Korea in order...
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Epidemiology of liver cancer in Korea

Kweon SS

The incidence rate of primary liver cancer in Korea, the majority of which is hepatocellular carcinoma, has been decreasing steadily since 1999. However, Korea still has one of the highest...
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2018 Korean Liver Cancer Association–National Cancer Center Korea Practice Guidelines for the Management of Hepatocellular Carcinoma

Korean Liver Cancer Association (KLCA), National Cancer Center (NCC), Goyang, Korea

Hepatocellular carcinoma (HCC) is the fifth most common cancer globally and the fourth most common cancer in men in Korea, where the prevalence of chronic hepatitis B infection is high...
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The Health Burden of Cancer Attributable to Obesity in Korea: A Population-Based Cohort Study

Lee JE, Nam CM, Lee SG, Park S, Kim TH, Park EC

PURPOSE: Considering the health impact of obesity and cancer, it is important to estimate the burden of cancer attributable to high body mass index (BMI). Therefore, the present study attempts...
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Implication of hepatocyte dedifferentiation in pathogenesis and treatment of hepatocellular carcinoma

Kim HS, Park EJ, Lee CW

Liver cancer is the fifth most common malignancy worldwide and the third most common cause of cancer-related death. Five hundred million individuals are infected by hepatitis B or C virus....
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Morbidity Profile of Cases Attended Oncology Center of Mansoura University (OCMU), Egypt: A Cross-Sectional Study

Elmetwaly , Emarah ZA, Abd Elhamied AEM, Hegazy MA, Kamel EA, Al-Wehedy

OBJECTIVES: In Egypt, the National Cancer Registry Program integrates hospital-based data from multiple Egyptian governorates to obtain representative rates. Unfortunately, Dakahlia (one of the largest Egyptian governorates) was not integrated...
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Emerging Role of Hepatobiliary Magnetic Resonance Contrast Media and Contrast-Enhanced Ultrasound for Noninvasive Diagnosis of Hepatocellular Carcinoma: Emphasis on Recent Updates in Major Guidelines

Kim TH, Yoon JH, Lee JM

Hepatocellular carcinoma (HCC) can be noninvasively diagnosed on the basis of its characteristic imaging findings of arterial phase enhancement and portal/delayed “washout” on computed tomography (CT) and magnetic resonance imaging...
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2018 Korean Liver Cancer Association–National Cancer Center Korea Practice Guidelines for the Management of Hepatocellular Carcinoma

Korean Liver Cancer Association (KLCA) and National Cancer Center (NCC), Korea. klca@livercancer.or.kr, jwpark@ncc.re.kr

Hepatocellular carcinoma (HCC) is the fifth most common cancer globally and the fourth most common cancer in men in Korea, where the prevalence of chronic hepatitis B infection is high...
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Cystic Degeneration of Hepatocellular Carcinoma Mimicking Mucinous Cystic Neoplasm

Lee J, Lee N, Yoon HK, Lee YJ, Park SJ

Spontaneous regression of tumors is an extremely rare event in hepatocellular carcinoma (HCC) with only a few reports available. With the accumulation of clinical information and tumor immunogenetics, several mechanisms...
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