J Korean Med Sci.  2000 Apr;15(2):240-242. 10.3346/jkms.2000.15.2.240.

A case report of primary T-cell lymphoma of the liver

• Kim HS
• Ko YH
• Ree HJ

• KMID: 648131
• DOI: http://doi.org/10.3346/jkms.2000.15.2.240

Abstract

The patient was a 50-year-old woman who presented intermittent mild fever with elevated liver enzymes for 12 years. The liver biopsy showed diffuse portal and sinusoidal involvement of lymphoid cells with minimal atypia and epithelioid histiocytic granuloma formation. Subsequent bone marrow biopsy showed lymphomatous involvement. The lymphocytes infiltrating the liver were reactive for T-cell marker and showed TCR gamma gene rearrangement. The patient was diagnosed as primary peripheral T-cell lymphoma of the liver. Indolent clinical course and resemblance with hepatitis were considered to be a rare and unique feature of this case.

Keyword

T-Cell Lymphoma; Liver

MeSH Terms

Case Report
DNA, Neoplasm/analysis
Female
Gene Rearrangement
Human
Liver Neoplasms/radiography
Liver Neoplasms/pathology*
Liver Neoplasms/genetics
Lymphoma, T-Cell/radiography
Lymphoma, T-Cell/pathology*
Lymphoma, T-Cell/genetics
Middle Age
Receptors, Antigen, T-Cell, gamma-delta/genetics
Tomography, X-Ray Computed