Korean J Radiol.  2008 Dec;9(6):559-562. 10.3348/kjr.2008.9.6.559.

Diffuse Hepatic Hemangiomatosis without Extrahepatic Involvement in an Adult Patient

• Kim EH
• Park SY
• Ihn YK
• Hwang SS

• KMID: 1118879
• DOI: http://doi.org/10.3348/kjr.2008.9.6.559

Abstract

We report an extremely rare case of a diffuse hepatic hemangiomatosis without extrahepatic involvement in an adult. The imaging findings of this tumor were similar to those of a hepatic hemangioma and included contrast enhancement with a centripetal filling pattern of the entire hepatic tumor on the delayed phase of a dynamic CT and inhomogeneous diffuse uptake of the entire tumor on blood-pool images obtained five hours later on a 99mTc-labeled red blood cell scan. Despite its rarity, diffuse hepatic hemangiomatosis can be suggested in adult patients with diffusely involved hepatic tumors showing the radiological findings of a hepatic hemangioma.

Keyword

Hemangioma, carvernous; Liver Neoplasms

MeSH Terms

Adult
Female
Gated Blood-Pool Imaging
Hemangioma/*diagnosis/pathology/ultrasonography
Humans
Liver Neoplasms/*diagnosis/pathology/ultrasonography
Tomography, X-Ray Computed

Figure

• 

  Fig. 1 Diffuse hepatic hemangiomatosis in 33-year-old woman. A. Ultrasonography indicates heterogeneous infiltrative hepatic tumor containing various-sized hypoechoic nodules. B. No remarkable tumor vascularity is observed, except for hepatic parenchymal vessels. C-F. Dynamic CT demonstrates early nodular contrast enhancement on arterial (D) and gradual centripetal pattern of contrast enhancement in diffuse infiltrating hepatic mass on portal (E) and delayed (F) phases. Neither intratumoral calcifications nor area of normalappearing intervening hepatic parenchymal vessels are visible. G. 99mTc-labeled red blood cell scan reveals heterogeneous uptake of radiopharmaceuticals throughout hepatic mass, involving whole liver on blood pool images. Diffuse tumor uptake is still noted on delayed scan obtained five hours later. H. Histological findings reveal endothelial cell proliferation and dilated blood channels (Hematoxylin & Eosin staining, × 200).

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