Osong Public Health Res Perspect.  2018 Jun;9(3):122-125. 10.24171/j.phrp.2018.9.3.07.

Case of Rickettsia typhi-induced Brain Abscess Mimicking Brain Tumor

Affiliations
  • 1Department of Neurology, Laboratory for Neurotherapeutics, Comprehensive Epilepsy Center, Center for Medical Innovations, Biomedical Research Institute, Seoul National University Hospital; Program in Neuroscience, Seoul National University College of Medicine, Seoul, Korea. stemcell.snu@gmail.com
  • 2Department of Neurology, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.

Abstract

Murine typhus is one of the most prevalent rickettsial infections in the world, caused by the bacterial genus Rickettsia. Though the disease manifests a relatively benign clinical course with fever, rash, and headache being the 3 classic symptoms, neurological complications may arise in patients that could become permanent. In this case study, a patient with a brain abscess caused by R typhi infection is described. Based upon the recent reemergence of arthropod-borne disease, the findings in this case are significant; R typhi can cause a brain abscess that mimics a brain tumor, which delays the diagnosis and appropriate management of the disease. Murine typhus should always be considered when performing the differential diagnosis of brain abscesses in South Korea.

Keyword

brain abscess; murine typhus; Rickettsia

MeSH Terms

Brain Abscess*
Brain Neoplasms*
Brain*
Diagnosis
Diagnosis, Differential
Exanthema
Fever
Headache
Humans
Korea
Rickettsia*
Typhus, Endemic Flea-Borne
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