Korean J Intern Med.  2018 Jul;33(4):829-836. 10.3904/kjim.2016.223.

Association between dietary intake and postlaparoscopic cholecystectomic symptoms in patients with gallbladder disease

Affiliations
  • 1Department of Food and Nutrition, Hanyang University College of Human Ecology, Seoul, Korea. yongsoon@hanyang.ac.kr
  • 2Department of Surgery, Hanyang University College of Medicine, Seoul, Korea.
  • 3Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.

Abstract

BACKGROUND/AIMS
After cholecystectomy, patients have reported postcholecystectomic syndromes such as abdominal symptoms, dyspepsia, and diarrhea, which suggest a relationship between cholecystectomic symptoms and diet, although the details of this association remain unclear. The present study investigated the hypothesis that dietary intake of nutrients and foods was significantly associated with postcholecystectomic syndromes.
METHODS
Gallstone patients (n = 59) who underwent laparoscopic cholecystectomy were enrolled, and dietary intake and clinical parameters were assessed immediately postcholecystectomy and 3 months later.
RESULTS
There were no significant differences in biochemical measurements or characteristics between symptomatic and asymptomatic patients. Immediately postcholecystectomy, there were no significant differences in consumption of nutrients or foods between symptomatic and asymptomatic patients. However, 3 months after cholecystectomy, symptomatic patients consumed more animal protein, cholesterol, and eggs, and fewer vegetables than did asymptomatic patients. Multivariable-adjusted regression analyses also indicated that the risk for symptoms was positively associated with intake of animal protein, cholesterol, and eggs, but negatively associated with intake of vegetables after adjusting for confounders. In addition, symptomatic patients consumed more bread-based breakfast foods, while asymptomatic patients consumed more rice.
CONCLUSIONS
Postcholecystectomic syndromes were positively associated with intake of cholesterol, animal protein, and eggs, and negatively associated with intake of vegetables, suggesting that diet was plays a role in postcholecystectomic syndromes.

Keyword

Diet; Gallstone; Postcholecystectomy syndrome; Follow-up studies

MeSH Terms

Animals
Breakfast
Cholecystectomy
Cholecystectomy, Laparoscopic
Cholesterol
Diarrhea
Diet
Dyspepsia
Eggs
Follow-Up Studies
Gallbladder Diseases*
Gallbladder*
Gallstones
Humans
Ovum
Postcholecystectomy Syndrome
Vegetables
Cholesterol
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