Korean J Fam Pract.  2020 Apr;10(2):143-148. 10.21215/kjfp.2020.10.2.143.

The Associations between Dietary Intake of N-3 Fatty Acids and 10-Year Cardiovascular Disease Risk: The Korea National Health and Nutrition Examination Survey, 2012–2016

• Kang S
• Kim Mj
• Kim Sj
• Park J
• An JY
• Choi M

• KMID: 2502323
• DOI: http://doi.org/10.21215/kjfp.2020.10.2.143

Abstract

Background
Dietary intake of n-3 fatty acids have been suggested for their protective role against cardiovascular disease. However, findings from recent studies have been inconsistent. Thus, we investigated the association between dietary intake of n-3 fatty acids and the 10-year risk of cardiovascular disease (CVD).
Methods
We analyzed data from 17,390 adults who were aged 30–64 years and free of CVD using the Korea National Health and Nutrition Examination Survey, 2012–2016. Dietary intake of n-3 fatty acids was calculated by using food-frequency questionnaire, and the 10 year risk of CVD was calculated by Framingham general cardiovascular disease risk score (2008) model. We analyzed the odds ratios (ORs) and 95% confidence intervals (CIs) from logistic regression to evaluate the association between dietary intake of n-3 fatty acids and the 10-year risk of CVD.
Results
Logistic regression anlaysis showed that dietary intake of n-3 fatty acids was not significantly associated with the 10-year risk of CVD, after adjusting for confounders (OR=0.91; 95% CI, 0.77–1.07). But higher dietary intake of n-3 fatty acids was associated with reduced the 10-year risk of CVD for the female (OR=0.74; 95% CI, 0.58–0.95).
Conclusion
Our research indicated no significant association between dietary intake of n-3 fatty acids and the 10-year risk of CVD. But the inverse association was observed in the female.

Keyword

Fatty Acids, Omega-3; Cardiovascular Disease; Risk Assessment; Primary Prevention