J Vet Sci.  2016 Jun;17(2):257-260. 10.4142/jvs.2016.17.2.257.

Clinical usefulness of post-operative 18F-fluorodeoxyglucose positron emission tomography-computed tomography in canine hemangiosarcoma

Affiliations
  • 1Veterinary Medical Imaging, College of Veterinary Medicine and BK 21 Plus Project Team, Chonnam National University, Gwangju 61186, Korea. imsono@chonnam.ac.kr
  • 2Department of Nuclear Medicine, Chonnam National University Hwasun Hospital, Hwasun 58128, Korea.
  • 3Laboratory of Veterinary Pathology, College of Veterinary Medicine and BK 21 Plus Project Team, Chonnam National University, Gwangju 61186, Korea.
  • 4Chonnam National University Veterinary Teaching Hospital, Gwangju 61186, Korea.

Abstract

This report describes the usefulness of positron emission tomography-computed tomography (PET-CT) for evaluating recurrent or residual tumors following surgery. CT and 18F-fluorodeoxyglucose PET-CT were pre- and post-operatively applied to multiple masses in a dog with hemangiosarcoma. The distinction between the left subcutaneous mass and the peritoneum was clarified on pre-operative CT examination, and malignancy was suspected based on PET-CT. A recurrent or residual tumor in the left subcutaneous region was suspected on post-operative PET-CT, and confirmed through histopathologic examination.

Keyword

18F-fluorodeoxyglucose; canine; computed tomography; hemangiosarcoma; positron emission tomography-computed tomography

Figure

  • Fig. 1 Pre- (A–D) and post- (E) operative computed tomography (CT) images. On transverse CT images, the left subcutaneous mass (*) showed heterogeneous enhancement at the arterial phase (A) and the contrast enhancement was persistent and increased at the venous phase (B). On the dorsally reformatted CT image (C), the mass displaced the peritoneum and left hepatic lobes (l) inward, but had smooth margins with no invasion of the abdominal cavity. (D) On the volume rendering image, the costal cartilage of the left 11th rib was lost (arrows), but bone structure was preserved without change. (E) On the post-operative transverse CT image, the left subcutaneous region (*) was swollen, with a similar density and contrast enhancement pattern, compared to the pre-operative CT images.

  • Fig. 2 Positron emission tomography and computed tomography (PET-CT) images using 18F-fluorodeoxyglucose. Pre- (left) and post- (right) operative maximum intensity projection views (A) showed abnormal hypermetabolic lesions (arrows), as well as physiological uptake (especially in the brain, heart, kidneys, urinary bladder, etc.). On each transverse plane of the PET-CT fusion images (B–G), all images were ordered in the cranial to caudal direction with pre- (left) and post- (right) operative images. There were multiple hypermetabolic lesions in the left infraspinatus muscle (B), sternal lymph node (C), diaphragmatic parietal pleura (D), and left subcutaneous (E), right abdominal (F), and perianal (G) areas (arrows). a, brain; b, injection site; c, heart; d, kidney; e, urinary bladder.


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