Gut Liver.  2017 Jul;11(4):520-527. 10.5009/gnl16330.

Comparison of the Efficacy and Safety of Single- versus Double-Balloon Enteroscopy Performed by Endoscopist Experts in Single-Balloon Enteroscopy: A Single-Center Experience and Meta-Analysis

• Kim TJ
• Kim ER
• Chang DK
• Kim YH
• Hong SN

• KMID: 2412232
• DOI: http://doi.org/10.5009/gnl16330

Abstract

BACKGROUND/AIMS
Studies concerning the efficacy and safety of single-balloon enteroscopy (SBE) compared with that of double-balloon enteroscopy (DBE) often appear to be conflicting. However, previous studies were performed by endoscopists who were less experienced in SBE compared with DBE.
METHODS
We performed a retrospective analysis of SBE and DBE data performed by a single enteroscopist, with expertise in SBE, using a prospective balloon-assisted enteroscopy registry from 2013 to 2015. Furthermore, we performed a comprehensive literature search and meta-analysis of available studies, including the current study, to clarify the efficacy and safety of SBE versus DBE.
RESULTS
A total of 65 procedures in 44 patients with SBE and 74 procedures in 69 patients with DBE were analyzed. There were no significant differences in diagnostic yield (61.1% vs 77.3%, respectively, p=0.397), therapeutic yield (39.1% vs 31.8%, respectively, p=0.548), and complication rate (4.4% vs 2.3%, p=1.000). In the meta-analysis, which included four randomized controlled trials and three observational studies, there were no significant differences in the pooled relative risk and odds ratio for diagnostic and therapeutic yield and complications of SBE compared with those of DBE.
CONCLUSIONS
The performance of SBE appears to be similar to that of DBE in terms of diagnostic and therapeutic yield and complications.

Keyword

Single-balloon enteroscopy; Double-balloon enteroscopy; Balloon-assisted enteroscopy; Meta-analysis

MeSH Terms

Adult
Aged
Clinical Competence/*statistics & numerical data
Comparative Effectiveness Research
Double-Balloon Enteroscopy/*statistics & numerical data
Female
Gastroenterologists/*statistics & numerical data
Humans
Intestinal Diseases/*surgery
Male
Middle Aged
Prospective Studies
Retrospective Studies
Single-Balloon Enteroscopy/*statistics & numerical data
Treatment Outcome