Gut Liver.  2016 May;10(3):399-405. 10.5009/gnl15188.

Factors Associated with Anxiety and Depression in Korean Patients with Inactive Inflammatory Bowel Disease

Affiliations
  • 1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea. diksmc.park@samsung.com

Abstract

BACKGROUND/AIMS
Psychological distress is highly prevalent in patients with inflammatory bowel disease (IBD). We evaluated the disease characteristics and socioeconomic factors associated with anxiety and depression in Korean patients with quiescent IBD.
METHODS
In total, 142 IBD patients (67 with Crohn's disease [CD] and 75 with ulcerative colitis [UC]) completed self-report questionnaires, including the Hospital Anxiety and Depression Score, the Modified Morisky Adherence Scale-8, the socioeconomic deprivation score, and the Crohn's and Colitis Knowledge Score questionnaires.
RESULTS
In the CD group, 30 patients (44%) were anxious, and 10 patients (15%) were depressed; in the UC group, 31 patients (41%) were anxious, and 18 patients (24%) were depressed. Using multivariate analysis, in the CD group, socioeconomic deprivation was associated with anxiety (p=0.03), whereas disease duration (p=0.04) and socioeconomic deprivation (p=0.013) were associated with depression. In the UC group, there was no significant independent predictor of anxiety and/or depression; however, low income tended to be associated with depression (p=0.096).
CONCLUSIONS
Despite clinical remission, a significant number of IBD patients present with anxiety and depression. IBD patients in remission, particularly those who are socioeconomically deprived, should be provided with appropriate psychological support.

Keyword

Inflammatory bowel diseases; Anxiety; Depression

MeSH Terms

Adult
Anxiety Disorders/ethnology/*etiology
Case-Control Studies
Colitis, Ulcerative/ethnology/*psychology
Crohn Disease/ethnology/*psychology
Depressive Disorder/ethnology/*etiology
Female
Humans
Income
Male
Republic of Korea/ethnology
Socioeconomic Factors
Surveys and Questionnaires
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