Psychiatry Investig.  2018 Feb;15(2):178-185. 10.30773/pi.2017.07.13.

Characteristics of Residual Symptoms in Korean Patients with Major Depressive Disorder: A Validation Study for the Korean Version of Depression Residual Symptom Scale

• Park SA
• Jeon SW
• Yoon HK
• Yoon SY
• Shin C
• Ko YH

• KMID: 2409427
• DOI: http://doi.org/10.30773/pi.2017.07.13

Abstract

OBJECTIVE
Residual symptoms of depression are related to more severe and chronic course of functional impairment with higher risk of relapse. The objective of this study was to validate, and determine psychometric properties of the Korean version of Depression Residual Symptom Scale (KDRSS).
METHODS
A total of 203 outpatients with recent episode of major depression based on DSM-IV criteria were enrolled in this study. They had been treated with antidepressants and assessed by KDRSS, Hamilton Depression Rating Scale-24 (HDRS-24), and Montgomery-Ã…sberg Depression Rating Scale (MARDS). The validity and reliability of KDRSS were assessed, including internal consistency reliability, concurrent validity, temporal stability, factorial validity, and discriminative validity.
RESULTS
Internal consistency (Cronbach's alpha=0.961), concurrent validity (MADRS: r=0.731, p < 0.01, HDRS-24: r=0.663, p < 0.01), and temporal stability (r=0.726, p < 0.01) of KDRSS were all excellent. KDRSS showed good discriminative validity based on MARDS. KDRSS consisted of one-factor structure accounting for 63.8% of total variance. All subjects except two in full remission group had one or more residual symptoms. In 7 subscales of KDRSS consisting of similar items respectively, "˜lack of energy' was the most commonly reported, followed by "˜increased emotionalism' in this group.
CONCLUSION
KDRSS is a useful and sensitive instrument for measuring residual depressive symptoms. Since some depressive symptoms including "˜lack of energy' and "˜increased emotionalism' in patients with full remission might be persistent during psychiatric intervention, these symptoms need to be focused on in clinical practice.

Keyword

Major depressive disorder; Remission; Depression residual symptom scale

MeSH Terms

Antidepressive Agents
Depression*
Depressive Disorder, Major*
Diagnostic and Statistical Manual of Mental Disorders
Humans
Outpatients
Psychometrics
Recurrence
Reproducibility of Results
Antidepressive Agents