Kidney Res Clin Pract.
2017 Mar;36(1):100-104. 10.23876/j.krcp.2017.36.1.100.
Syndrome of inappropriate antidiuretic hormone secretion associated with seronegative neuromyelitis optica spectrum disorder
- Affiliations
-
- 1Department of Medicine, Graduate School, Kyung Hee University, Seoul, Korea.
- 2Division of Nephrology, Department of Internal Medicine, Kyung Hee University Medical Center, Seoul, Korea. aprilhwan@naver.com
- 3Department of Neurology, Kyung Hee University Medical Center, Seoul, Korea.
- KMID: 2409395
- DOI: http://doi.org/10.23876/j.krcp.2017.36.1.100
Abstract
- The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a potential cause of hyponatremia of the central nervous system (CNS). Although SIADH has been reported to be associated with many other central nervous disorders, its association with neuromyelitis optica (NMO) or NMO spectrum disorders are rare. NMO is a demyelinating disorder characterized by optic neuritis and transverse myelitis. Aquaporin-4 (AQP4), which is the target antigen for a NMO autoantibody, is the predominant CNS water channel. However, some NMO patients show seronegative AQP4 antibody results. The spectrum of NMO has been changed, and new findings about the disease have been reported. Here, we report a case of seronegative NMO spectrum disorder associated with SIADH.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A Case of Cerebral Salt Wasting Syndrome in Neuromyelitis Optica Spectrum Disorder
- Early relapse after rituximab treatment in a patient with seronegative neuromyelitis optica spectrum disorder: a case report
- Postpartum Relapse of Neuromyelitis Optica Spectrum Disorder after a Long Period of Spontaneous Remission
- Late-onset Seronegative Neuromyelitis Optica Spectrum Disorder Mimicking Wernicke Encephalopathy
- Differential Diagnosis between Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder
