Kidney Res Clin Pract.  2018 Mar;37(1):85-88. 10.23876/j.krcp.2018.37.1.85.

Use of fludrocortisone for intradialytic hypotension

• Seo Y
• Jeung S
• Kang SM
• Yang WS
• Kim H
• Kim SB

• KMID: 2409378
• DOI: http://doi.org/10.23876/j.krcp.2018.37.1.85

Abstract

Intradialytic hypotension during dialysis adversely affects a patient's prognosis and increases mortality. We report a case in which intradialytic hypotension that persisted after the administration of midodrine was relieved after the use of fludrocortisone. Administration of 0.2 mg of fludrocortisone occurred 30 minutes before dialysis. We compared 45 sessions of dialysis without fludrocortisone administration and 45 sessions of dialysis with fludrocortisone administration in one patient. The number of times in which systolic blood pressure became lower than 80 mmHg and the number of early terminations of dialysis due to a decrease in systolic blood pressure were higher in the sessions without fludrocortisone administration than in the sessions with fludrocortisone administration (P < 0.05). Fludrocortisone may be helpful for the treatment of intradialytic hypotension that does not respond to midodrine administration.

Keyword

Fludrocortisone; Hypotension; Midodrine; Renal dialysis

MeSH Terms

Blood Pressure
Dialysis
Fludrocortisone*
Humans
Hypotension*
Midodrine
Mortality
Prognosis
Renal Dialysis
Fludrocortisone
Midodrine