Clin Exp Reprod Med.  2018 Mar;45(1):44-47. 10.5653/cerm.2018.45.1.44.

Successful onco-testicular sperm extraction from a testicular cancer patient with a single testis and azoospermia

• Kuroda S
• Kondo T
• Mori K
• Yasuda K
• Asai T
• Sanjo H
• Yakanaka H
• Takeshima
• Kawahara T
• Kato Y
• Miyoshi Y
• Uemura H
• Iwasaki A
• Yumura Y

• KMID: 2408576
• DOI: http://doi.org/10.5653/cerm.2018.45.1.44

Abstract

Onco-testicular sperm extraction is used to preserve fertility in patients with bilateral testicular tumors and azoospermia. We report the case of a testicular tumor in the solitary testis of a patient who had previously undergone successful contralateral orchiectomy and whose sperm was preserved by onco-testicular sperm extraction. A 35-year-old patient presented with swelling of his right scrotum that had lasted for 1 month. His medical history included a contralateral orchiectomy during childhood. Ultrasonography revealed a mosaic echoic area in his scrotum, suggesting a testicular tumor. The lesion was palpated within the normal testicular tissue along its edge and semen analysis showed azoospermia. Radical inguinal orchiectomy and onco-testicular sperm extraction were performed simultaneously. Motile spermatozoa were extracted from normal seminiferous tubules under microscopy and were frozen. Eventual intracytoplasmic sperm injection using the frozen spermatozoa is planned. Onco-testicular sperm extraction is an important fertility preservation method in patients with bilateral testicular tumors or a history of a previous contralateral orchiectomy.

Keyword

Male infertility; Testicular neoplasms; Testicular sperm retrieval

MeSH Terms

Adult
Azoospermia*
Fertility
Fertility Preservation
Humans
Infertility, Male
Male
Methods
Microscopy
Orchiectomy
Scrotum
Semen Analysis
Seminiferous Tubules
Sperm Injections, Intracytoplasmic
Sperm Retrieval
Spermatozoa*
Testicular Neoplasms*
Testis*
Ultrasonography