J Korean Neurosurg Soc.  2018 Jan;61(1):1-9. 10.3340/jkns.2017.0505.010.

Posttraumatic Delayed Vertebral Collapse : Kummell's Disease

• Lim J
• Choi SW
• Youm JY
• Kwon HJ
• Kim SH
• Koh HS

• KMID: 2403517
• DOI: http://doi.org/10.3340/jkns.2017.0505.010

Abstract

Posttraumatic delayed vertebral collapse, known as Kummell's disease, is increasing in number of patients. This disease is already progressive kyphosis due to vertebral collapse at the time of diagnosis and it causes intractable pain or neurologic deficit due to intravertebral instability. Treatment is very difficult after progression of the disease, and the range of treatment, in hospital day, and cost of treatment are both increased. Clinical features, pathogenesis and radiologic findings of these disease groups were reviewed to determine risk factors for delayed vertebral collapse. The purpose of this article is to suggest appropriate treatment before vertebral collapse for patients with osteoporotic vertebral compression fracture who have risk factors for posttraumatic delayed vertebral collapse.

Keyword

Osteoporosis; Vertebral fracture; Osteonecrosis; Intravertebral cleft; Kummell's disease

MeSH Terms

Diagnosis
Fractures, Compression
Humans
Kyphosis
Neurologic Manifestations
Osteonecrosis
Osteoporosis
Pain, Intractable
Risk Factors

Figure

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  Fig. 1 Case 1. A 62-year-old woman was admitted with severe backache who was suffering from rheumatoid arthritis relying on prednisolone for many years. She was diagnosed with compression fracture of T12. Her had appearance resembling that of the Cushing’s, bone mineral density examination showed severe osteoporosis, T score of -3.7. She was followed for 3 weeks with conservative treatment and osteoanabolic agent. However, T12 vertebral compression aggravated in follow up X-ray images and vertebroplasty was performed. However simple radiography, 1 month after the vertebroplasty, showed gradual progression of compression fracture and kyphosis of the T12 vertebrae but the clinical symptoms subsided, so progressive kyphosis was followed up without additional treatment. A : Serial simple spine lateral radiography showed compression fracture of T12 and progressive kyphosis. B : MRI showed high SI in fat suppressed T2WI and diffuse low SI in T1WI of T12. As well as, MRI revealed that the fluid content of the superior endplate of T12 high SI in T2WI and the low SI area of necrotic content (black arrows : IVC sign) and enhancing vertebral body in T1WI enhanced image. C : Postoperative serial simple radiographys showed progressive kyphosis. MRI : magnetic resonance image, IVC : intraverteral cleft.

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  Fig. 2 A 77-year-old man presented with persistent lumbago, progressive kyphosis and radiating pain on both lower extremities lasting about 3 months after minor trauma. He underwent conservative treatment with diagnosis of L1 compression fracture 2 months ago. A : A transverse radiolucent line of IVC sign (black arrow) was observed in anteroposterior view. And the intravertebral pseudoarthrosis and IVC sign (black arrows) were observed in the flexion-extension view. B : Spine MRI showed that typical IVC sign (white arrows) and ventral portion of spinal cord was compressed due to kyphosis. At first, vertebral body replacement was considered, but long level posterolateral fusion was performed due to elder and dementia. C : The restoration of the L1 body was observed in the postoperative image. However, recollapse of the restored L1 body, L3 screw loosening and posterior pull back were observed in the image 1 month after the fusion. AP : anteroposterior view, Lat. : lateral view, IVC : intraverteral cleft, MRI : magnetic resonance image.

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  Fig. 3 A 74-year-old woman presented with persistent back pain that had fallen 2 weeks ago. Radiologic examination at the time of admission revealed recent first lumbar compression fracture (A and B) and the patient underwent vertebroplasty (C). Her symptoms were improved and she was discharged with orthrosis and biphosphonate medication. Four months later, she revisited with progressive kyphosis, persistant backache and both lower leg weaknesses. Intravertebral instability at L1 body was suspected on the thoracolumbar flexion/extension simple radiographys (C). Dynamic spine CT showed intravertebral instability at L1 and compressed thecal sac due to fractured bony fragement of L1 (D). In MRI, there was no accurate intravertebral vaccum cleft, and compressed thecal sac was observed. We thought that her pain was caused by intravertebral instability, progressive neurologic deficit was caused by more protrusion of fractured bony fragment at flexion or weight bearing. We performed L1 corpectomy with mesh cage insertion and posterolateral fusion via posterior approach (E). Neurologic deficit and persistent backache disappeared. VP : vertebroplasty, CT : computerized tomography, MRI : magnetic resonance image.

Reference

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