J Nutr Health.  2017 Dec;50(6):565-577. 10.4163/jnh.2017.50.6.565.

Association between nutrient intake and serum high sensitivity C-reactive protein level in Korean adults: Using the data from 2015 Korea National Health and Nutrition Examination Survey

Affiliations
  • 1Department of Food and Nutrition, Chungnam National University, Daejeon 34134, Korea. jacho@cnu.ac.kr
  • 2Department of Food and Nutrition, Hannam University, Daejeon 34054, Korea.

Abstract

PURPOSE
There have been limited studies investigating the relationship between high-sensitivity C-reactive protein (hsCRP), metabolic diseases, and dietary factors in Korean adults. Here, we examined the association between nutrient intake and serum hsCRP among Korean adults.
METHODS
Using data on 2,624 healthy Korean adults (1,537 women and 1,087 men) from the 2015 Korea National Health and Nutrition Examination Survey, demographic, anthropometric, biochemical, and dietary factors were analyzed once the subjects were grouped into either sex, age, or BMI. Nutrient intake was evaluated using the dietary data obtained by one-day 24-hour recall. Based on the guidelines of the US Centers for Disease Control and Prevention and the American Heart Association, hsCRP level was classified as HCRPG (High CRP Group, hsCRP > 1 mg/L) and LCRPG (Low CRP Group, hsCRP ≤ 1 mg/L). Proc surveyreg procedure was performed to examine the associations between nutrient intake and hsCRP after adjustment for potential confounding variables.
RESULTS
The average hsCRP level of healthy Korean adults was 0.95 ±0.03 mg/L (0.97 ±0.04 mg/L in men, 0.92 ±0.05 mg/L in women). Obese subjects had significantly higher hsCRP than non-obese subjects in both sexes. The hsCRP level was positively associated with current smoking, physical inactivity, BMI, waist circumference, fasting blood glucose, triglycerides, total cholesterol, LDL-cholesterol, and blood pressure and inversely associated with HDL-cholesterol. LCRPG had significantly higher intake of dietary fiber compared to HCRPG in women. High hsCRP level was associated with more dietary cholesterol intake but less omega-3 fatty acid intake among subjects aged ≥ 50y. HCRPG of obese subjects had higher intakes of fat and saturated fatty acid than LCRPG.
CONCLUSION
The hsCRP level is closely associated with several lifestyle variables and nutrient intake in healthy Korean adults. Individuals with high hsCRP level show low intakes of dietary fiber and omega-3 fatty acids but high intakes of dietary fat and cholesterol. Our findings suggest that a potential anti-inflammatory role for nutrients and lifestyle in the Korean adult population.

Keyword

hsCRP; dietary fiber; fat; cholesterol; omega-3 fatty acid

MeSH Terms

Adult*
American Heart Association
Blood Glucose
Blood Pressure
C-Reactive Protein*
Centers for Disease Control and Prevention (U.S.)
Cholesterol
Cholesterol, Dietary
Confounding Factors (Epidemiology)
Dietary Fats
Dietary Fiber
Fasting
Fatty Acids, Omega-3
Female
Humans
Korea*
Life Style
Male
Metabolic Diseases
Nutrition Surveys*
Smoke
Smoking
Triglycerides
Waist Circumference
Blood Glucose
C-Reactive Protein
Cholesterol
Cholesterol, Dietary
Dietary Fats
Fatty Acids, Omega-3
Smoke
Triglycerides
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