Korean J Fam Pract.  2021 Jun;11(3):197-203. 10.21215/kjfp.2021.11.3.197.

Association between Carbonated Beverage Intake and High-Sensitivity C-Reactive Protein in Korean Adults

• Cha J
• Oh MJ
• Jang M
• Jo Y

• KMID: 2516844
• DOI: http://doi.org/10.21215/kjfp.2021.11.3.197

Abstract

Background
The purpose of this study was to evaluate the association between carbonated beverage intake and high-sensitivity C-reactive protein (hs-CRP) in Korean adults. Sugar consumption by Korean adults has increased, and carbonated beverages make up a large percentage of that increase. Hs-CRP is a clinically applicable marker that provides evaluation for cardiovascular disease (CVD) risk and prognosis.
Methods
We included 3,991 adults (aged ≥19 years) from the 2015 and 2016 Korea Health and Nutrition Examination Survey. The frequency of carbonated beverage intake was classified into four categories: 1) none; 2) 1–3 times a month; 3) 1–6 times a week; and 4) 1–3 times a day. The cutoff value for hs-CRP was referenced from the American Heart Association (AHA)/Centers for Disease Control and Prevention (CDC). Multinomial logistic regression analysis was conducted to evaluate the association between carbonated beverage intake and hs-CRP.
Results
The multinomial-adjusted odds ratio for hs-CRP greater than 3 mg/L was 1.71 (95% confidence interval, 1.12–2.61) for those with a carbonated beverage intake of 1–6 times a week and 3.10 (95% confidence interval, 1.34–7.16) for those with a carbonated beverage intake of 1–3 times a day.
Conclusion
This study shows that carbonated beverage intake may be associated with the increase of hs-CRP.

Keyword

Carbonated Beverage; Sugar-Sweetened Beverage; C-Reactive Protein; Cardiovascular Diseases