World J Mens Health.  2017 Dec;35(3):163-169. 10.5534/wjmh.17011.

Efficacy of Holmium Laser Enucleation of the Prostate in Patients with a Small Prostate (≤30 mL)

• Park S
• Kwon T
• Park S
• Moon KH

• KMID: 2398565
• DOI: http://doi.org/10.5534/wjmh.17011

Abstract

PURPOSE
We investigated the effects of holmium laser enucleation of the prostate (HoLEP) in patients with a small prostate (≤30 mL) in whom medical treatment was ineffective.
MATERIALS AND METHODS
Data from 132 patients who underwent HoLEP by a single surgeon between 2012 and 2015 were retrospectively analyzed. All patients received benign prostatic hyperplasia medication for at least 6 months before surgery. The patients were divided into 2 groups according to prostate size: group 1, ≤30 mL (n=30); and group 2, >30 mL (n=102). Clinical characteristics and the International Prostate Symptom Score (IPSS), including quality of life (QoL), peak urinary flow rate (Qmax), and postvoid residual urine (PVR), before surgery and 3 months postoperatively, were compared between the 2 groups.
RESULTS
In group 1, the IPSS, QoL, and PVR significantly decreased and the Qmax significantly increased 3 months after surgery. The voiding subscore also significantly decreased 3 months after surgery (p < 0.001), but the storage subscore was not significantly different (p=0.055). In group 2, hemoglobin, the IPSS, QoL, and PVR significantly decreased and the Qmax significantly increased 3 months after surgery. In these patients, both the storage subscore and voiding subscore significantly decreased after surgery (both p < 0.001). There were no significant differences between the groups in hemoglobin, IPSS, QoL, Qmax, and PVR either before or 3 months after surgery.
CONCLUSIONS
When other medical treatments are ineffective, HoLEP is an effective intervention for patients with a small prostate.

Keyword

Holmium; Lasers; Prostate; Transurethral resection of prostate; Treatment outcome

MeSH Terms

Holmium*
Humans
Lasers, Solid-State*
Prostate*
Prostatic Hyperplasia
Quality of Life
Retrospective Studies
Transurethral Resection of Prostate
Treatment Outcome
Holmium

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