Korean J Thorac Cardiovasc Surg.  2017 Oct;50(5):378-381. 10.5090/kjtcs.2017.50.5.378.

Large Atrial Septal Defect Closure in a Patient with Severe Pulmonary Arterial Hypertension

Affiliations
  • 1Thoracic and Cardiovascular Surgery Division, Dr. Sardjito General Hospital, Universitas Gadjah Mada, Indonesia. supomo.tkv@mail.ugm.ac.id
  • 2Department of Surgery and Department of Cardiology and Vascular Medicine, Dr. Sardjito General Hospital, Universitas Gadjah Mada, Indonesia.

Abstract

Patients with an atrial septal defect (ASD) and severe pulmonary arterial hypertension (PAH) are considered ineligible for defect closure surgery because of the risk of right ventricular decompensation and death after the operation. We report the case of a patient with large ASD and severe PAH who was able to undergo defect closure surgery successfully following long-term use of combined oral sildenafil and beraprost.

Keyword

Atrial heart septal defects; Beraprost; Congenital heart disease; Pulmonary hypertension; Sildenafil citrate

MeSH Terms

Heart Defects, Congenital
Heart Septal Defects, Atrial*
Humans
Hypertension*
Hypertension, Pulmonary
Sildenafil Citrate
Sildenafil Citrate
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