Yonsei Med J.  2008 Feb;49(1):163-166.

Rescue Use of Tirofiban for Acute Carotid In-Stent Thrombosis

• Seo KD
• Lee KO
• Kim DJ
• Lee KY

Abstract

Carotid artery stenting is widely performed for extracranial carotid artery stenosis. In-stent thrombosis is a rare but potentially devastating complication. We present a case of acute in-stent thrombosis immediately following stent insertion and post-balloon dilatation in a 64-year-old male. Thrombosis was successfully treated by intravenous tirofiban, a glycoprotein IIb/IIIa receptor inhibitor.

Keyword

Glycoprotein IIb/IIIa receptor inhibitor; carotid artery stent; thrombosis

MeSH Terms

Acute-Phase Reaction/*drug therapy/*pathology
Angiography
Carotid Artery Diseases/*drug therapy/*pathology
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Stents
Thrombosis/*drug therapy/*pathology
Tyrosine/*analogs & derivatives/therapeutic use

Figure

• 

  Fig. 1 Digital subtraction cerebral angiography shows left common carotid artery stenosis (A). Immediately after stent insertion and balloon dilatation in-stent thrombus (arrow) is seen (B). Thrombus disappears after intravenous tirofiban infusion (C).

• 

  Fig. 2 Brain diffusion-weighted MRI shows small high signal lesions (arrow) in right occipital lobe.

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