Clin Exp Otorhinolaryngol.  2017 Sep;10(3):221-227. 10.21053/ceo.2016.00787.

Association Between Hearing Impairment and Albuminuria With or Without Diabetes Mellitus

• Jung DJ
• Lee JH
• Kim T
• Kim HG
• Lee JY
• Lee KY

• KMID: 2395735
• DOI: http://doi.org/10.21053/ceo.2016.00787

Abstract

OBJECTIVES
Few studies have evaluated the accurate association between hearing loss (HL) and albuminuria in patients with or without diabetes mellitus (DM). The aim of our study was to identify the clinical effects of albuminuria on HL with or without DM.
METHODS
This study included 9,762 patients from the Korean National Health and Nutrition Examination Survey between 2011 and 2013. Participants were divided into 4 groups based on DM and urine albumin/creatinine ratio levels: group 1 included participants with neither DM nor albuminuria, group 2 included participants without DM and with albuminuria, group 3 included patients with DM and without albuminuria, and group 4 included patients with both DM and albuminuria. The low- or mid-frequency and high-frequency, and average hearing threshold values were obtained.
RESULTS
There were 7,508, 545, 1,325, and 384 participants in groups 1, 2, 3, and 4, respectively. Univariate and multivariate analyses showed that the 3 hearing thresholds in group 1 were the lowest and those in group 4 were the highest among the 4 groups. No significant differences were observed in those thresholds between groups 2 and 3. Group 4 was associated with HL compared with the other groups, but moderate to severe HL was not associated with DM or albuminuria.
CONCLUSION
The presence of albuminuria was associated with a modest effect on hearing thresholds regardless of presence of DM.

Keyword

Diabetes Mellitus; Albuminuria; Hearing Threshold; Hearing Loss

MeSH Terms

Albuminuria*
Diabetes Mellitus*
Hearing Loss*
Hearing*
Humans
Multivariate Analysis
Nutrition Surveys

Figure

• 

  Fig. 1. Hearing thresholds according to diabetes mellitus and albuminuria. The multivariate analysis was adjusted for age, sex, high-density lipoprotein cholesterol levels, triglyceride levels, estimated glomerular filtration rate, systolic blood pressure, diastolic blood pressure, body mass index, alcohol consumption, smoking behavior, glycated hemoglobin levels, and exposure to explosives or occupational noise (*P<0.05 compared with group 1; †P<0.05 compared with groups 1, 2, and 3). The data are expressed as mean and standard error. AHT, average hearing threshold.

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