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Framingham Risk Score Assessment in Subjects with Pre-diabetes and Diabetes: A Cross-Sectional Study in Korea

Kwon HS, Song KH, Yu JM, Kim DS, Shon HS, Ahn KJ, Choi SH, Ko SH, Kim W, Lee KH, Nam-Goong IS, Park TS

Background: This study aimed to evaluate cardiovascular risk in subjects with pre-diabetes and diabetes in Korea. Methods: In this pan-Korean, non-interventional, cross-sectional study, data were collected from medical records of 10...
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Monogenic diabetes mellitus and clinical implications of genetic diagnosis

Kang E, Chung LY, Kim YJ, Oh KE, Rhie YJ

Monogenic diabetes mellitus, which is diabetes caused by a defect in a single gene that is associated with β cell function or insulin action, accounts for 1% to 6% of...
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Assessment of Insulin Secretion and Insulin Resistance in Human

Park SY, Gautier JF, Chon S

The impaired insulin secretion and increased insulin resistance (or decreased insulin sensitivity) play a major role in the pathogenesis of all types of diabetes mellitus (DM). It is very important...
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A Century of Progress in Diabetes Care with Insulin: A History of Innovations and Foundation for the Future

Lee SH, Yoon KH

The year 2021 marks the 100th anniversary of the discovery of insulin, which has greatly changed the lives of people with diabetes and become a cornerstone of advances in...
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Hyperglycemic Hemichorea: A Case Series

Moon S, Kim HE, Oh TJ, Ahn CH, Choi SH, Jang HC

Hemichorea has been reported in subjects with hyperglycemia and the recurrent was rarely reported. We identified clinical presentation and course of hypeglycemic hemichorea in six cases, one of whom experienced...
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Real-World Efficacy and Safety of Dulaglutide in Korean Patients with Type 2 Diabetes Mellitus: A Retrospective Study in a Tertiary Referral Center

Yoon JH, Hong AR, Choi W, Park JY, Kim HK, Kang HC

This study was conducted to evaluate the efficacy and safety of once-weekly dulaglutide therapy as add-on to oral antidiabetic drugs (OADs) and basal insulin in Korean patients with type 2...
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Antidiabetic Activity of Nigella Sativa (Black Seeds) and Its Active Constituent (Thymoquinone) – A Review of Human and Experimental Animal Studies

Maideen NMP

The use of herbal medicine to manage chronic conditions including diabetes has become a recent global trend. Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia. The...
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Young-onset type 2 diabetes in South Korea: a review of the current status and unmet need

Yang YS, Han K, Sohn TS, Kim NH

The prevalence of young-onset (diagnosis at age < 40 years) type 2 diabetes mellitus (T2DM) is increasing globally. Young-onset T2DM has a common pathophysiology of glucose dysregulation as in late-onset...
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Effects of Social Distancing on Diabetes Management in Older Adults during COVID-19 Pandemic

Shin SM, Oh TJ, Choi SH, Jang HC

Background: On March 22, 2020, intense social distancing (SD) was implemented in Korea to prevent the spread of coronavirus disease 19 (COVID-19). This study examined the impact of SD on...
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Effects of crocin and metformin on methylglyoxal-induced reproductive system dysfunction in diabetic male mice

Khorasani MK, Ahangarpour A, Khorsandi L

Objective: This study investigated the effect of crocin in methylglyoxal (MGO)-induced diabetic male mice. Methods: Seventy 1-month-old male NMRI mice weighing 20–25 g were divided into seven groups (n=10): sham, MGO...
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Effects of Advanced Glycation End Products on Differentiation and Function of Osteoblasts and Osteoclasts

Park SY, Choi KH, Jun JE, Chung HY

Background: Risk of fragility fractures increases in patients with diabetes mellitus, independent of bone mineral density. In the present study, the effects of advanced glycation end products (AGEs) on differentiation...
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Treatment Patterns of Type 2 Diabetes Assessed Using a Common Data Model Based on Electronic Health Records of 2000–2019

Lee KA, Jin HY, Kim YJ, Im YJ, Kim EY, Park TS

Background: Real-world data analysis is useful for identifying treatment patterns. Understanding drug prescription patterns of type 2 diabetes mellitus may facilitate diabetes management. We aimed to analyze treatment patterns of type...
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Appraisal of Guidelines for the Management of Blood Pressure in Patients with Diabetes Mellitus: The Consensuses, Controversies and Gaps

Liu M, Zhang S, Chen X, Guo Y, Zhong X, Xiong Z, Lin Y, Zhou H, Huang Y, Zhang Z, Wang L, Zhuang X, Liao X

Background: Currently available guidelines contain conflicting recommendations on the management of blood pressure (BP) in patients with diabetes mellitus (DM). Therefore, it is necessary to appraise the guidelines and summarize...
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Screening Tools Based on Nomogram for Diabetic Kidney Diseases in Chinese Type 2 Diabetes Mellitus Patients

Wang G, Wang B, Qiao G, Lou H, Xu F, Chen Z, Chen S

Background: The influencing factors of diabetic kidney disease (DKD) in Chinese patients with type 2 diabetes mellitus (T2DM) were explored to develop and validate a DKD diagnostic tool based on...
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High Incidence of Chronic Kidney Disease among Iranian Diabetic Adults: Using CKD-EPI and MDRD Equations for Estimated Glomerular Filtration Rate

Moazzeni SS, Arani RH, Hasheminia M, Tohidi M, Azizi F, Hadaegh F

Background: To investigate the population based incidence rate of chronic kidney disease (CKD) and its potential risk factors among Iranian diabetic adults during over 14 years of follow-up. Methods: Two different...
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Albuminuria Is Associated with Steatosis Burden in Patients with Type 2 Diabetes Mellitus and Nonalcoholic Fatty Liver Disease

Han E, Kim MK, Jang BK, Kim HS

Background: This study aimed to investigate the association between hepatic steatosis burden and albuminuria in Korean patients with type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease (NAFLD). Methods: We...
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Efficacy and Safety of Treatment with Quadruple Oral Hypoglycemic Agents in Uncontrolled Type 2 Diabetes Mellitus: A Multi-Center, Retrospective, Observational Study

Moon JS, Suh S, Kim SS, Jin HY, Kim JM, Jang MH, Lee KA, Lee JH, Chung SM, Lyu YS, Kim JH, Kim SY, Jang JE, Kim TN, Kim SW, Jeon E, Cho NH, Kim MK, Kim HS, Nam-Goong IS, Kim ES, Chung JO, Cho DH, Lee CW, Kim YI, Chung DJ, Won KC, Kim IJ, Park TS, Kim DK, Shon H

Background Only few studies have shown the efficacy and safety of glucose-control strategies using the quadruple drug combination. Therefore, the aim of the present study was to investigate the usefulness of...
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Mediating Effect of Acceptance Action in relationship between Diabetes Self-Stigma and Quality of Life in People with Diabetes in Korea

Seo K

Purpose: This study was done to investigate the mediating effects of acceptance action on the relationship between diabetes self-stigma and quality of life in diabetes patients. Methods: For this study a...
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Efficacy of Ulinastatin and Sulforaphane Alone or in Combination in Rat Model of Streptozotocin Diabetes Induced Vascular Dementia

Sharma P, Kaushik P, Jain S, Sharma BM, Awasthi R, Kulkarni GT, Sharma B

Objective: Vascular Dementia (VaD), is associated with metabolic conditions. Diabetes is a major risk factor for the development of VaD. This study investigates the efficacy of ulinastatin (UTI) and sulforaphane...
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Research Trend on Diabetes Mobile Applications: Text Network Analysis and Topic Modeling

Park S, Kwak E, Kim Y

Purpose: The aim of this study was to identify core keywords and topic groups in the ‘Diabetes mellitus and mobile applications’ field of research for better understanding research trends in...
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