Korean J Med.  2014 Dec;87(6):686-689. 10.3904/kjm.2014.87.6.686.

Dyslipidemia Treatment in Diabetes Mellitus Patients

• Kim SR

• KMID: 2269363
• DOI: http://doi.org/10.3904/kjm.2014.87.6.686

Abstract

Cardiovascular disease (CVD) is the major cause of mortality and morbidity in patients with type 2 diabetes mellitus. The increased risk of CVD in subjects with type 2 diabetes mellitus involves multiple factors, including hypertension, smoking, albuminuria, and hypercholesterolemia. Of these, hypercholesterolemia is amenable to intervention. A large body of research ranging from molecular to population studies indicates that elevated low-density-lipoprotein cholesterol (LDL-C) is a major predictor of CVD, including in the population with diabetes. Despite available therapies and increased attention to hypercholesterolemia, many patients fail to achieve the LDL-C goals. A patient-tailored approach to dyslipidemia therapy, as determined by baseline LDL-C levels, is an effective strategy for achieving target LDL-C levels.

Keyword

Type 2 diabetes mellitus; Cardiovascular disease; Hypercholesterolemia; LDL cholesterol

MeSH Terms

Albuminuria
Cardiovascular Diseases
Cholesterol
Cholesterol, LDL
Diabetes Mellitus*
Diabetes Mellitus, Type 2
Dyslipidemias*
Humans
Hypercholesterolemia
Hypertension
Mortality
Smoke
Smoking
Cholesterol
Cholesterol, LDL
Smoke