Korean J Med Mycol.  2017 Sep;22(3):117-121. 10.17966/KJMM.2017.22.3.117.

Late Onset Candida albicans Spondylodiscitis Following Candidemia: A Case Report

Affiliations
  • 1Department of Neurosurgery, Pusan National University Hospital, Busan, Korea.
  • 2Department of Neurosurgery, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea. cmcspinehwan@catholic.ac.kr
  • 3Department of Internal Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.

Abstract

Candida albicans infections of the spine are relatively uncommon in spite of the increasing frequency of predisposing factors. Moreover, late onset spondylodiscitis after bloodstream candidiasis is extremely rare. A 66-year-old woman to have been underwent chemotherapy was diagnosed with candidemia. Antifungal agent was administrated until two weeks after no detection of fungus in the blood culture. The chemotherapy was continued. But, she was hospitalized due to abdominal pain and diarrhea. Pseudomembranous colitis was diagnosed. After metronidazole administration, she was improved and discharged. However, she revisited because of back pain and fever. Spondylitis and discitis on the 10th~11th thoracic spine was shown in magnetic resonance images. Open curettage and spinal stabilization was performed. C. albicans was identified. Antifungal agent was administrated and the patient improved well postoperatively. We present a rare case of late onset Candida spondylodiscitis after candidemia with review of the literatures.

Keyword

Candida albicans; Candidemia; Spondylitis; Discitis
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