Allergy Asthma Immunol Res.  2016 May;8(3):181-190. 10.4168/aair.2016.8.3.181.

A Comprehensive Review of the Treatment of Atopic Eczema

• Lee JH
• Son SW
• Cho SH

• KMID: 2391037
• DOI: http://doi.org/10.4168/aair.2016.8.3.181

Abstract

Atopic eczema (AE) is a chronic, inflammatory skin disorder which usually develops in early childhood. In spite of intensive investigations, the causes of AE remain unclear, but are likely to be multifactorial in nature. Environmental factors or genetic-environmental interactions seem to play a key role in disease progression. Among various measures of AE managment, cutaneous hydration, which improves barrier function and relieve itchiness, may be helpful to reduce the need for topical steroid use and therefore should be used as a basic treatment. Avoiding aggravating factors is also a basic treatment of AE. Standard medical treatment with a pharmacologic approach may be necessary if basic treatment fails to control symptoms satisfactorily. Recently, more attention is given to a proactive therapeutic by regular intermittent application of low potency steroids or topical calcineurin inhibitors to prevent new flares. Furthermore, various targeted biologics are being introduced for AE control and are proposed as promising therapies. This paper provides a summary of the recent literature on the manangement of AE and a treatment guideline.

Keyword

Eczema; atopic dermatitis; atopic eczema; treatment; prevention; epidemiology

MeSH Terms

Biological Products
Calcineurin
Dermatitis, Atopic*
Disease Progression
Eczema
Epidemiology
Skin
Steroids
Biological Products
Calcineurin
Steroids

Figure

• 

  Figure An algorithm for the treatment of atopic eczema.

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