Transl Clin Pharmacol.  2017 Sep;25(3):125-133. 10.12793/tcp.2017.25.3.125.

Pharmacometric models simulation using NONMEM, Berkeley Madonna and R

• Park WS

• KMID: 2390931
• DOI: http://doi.org/10.12793/tcp.2017.25.3.125

Abstract

In this tutorial, we introduce a differential equation simulation model for use in pharmacometrics involving NONMEM, Berkeley Madonna, and R. We report components of the simulation code and similarities/differences between software, rather than how to use each software. Depending on the purpose of the simulation, an appropriate tool can be selected for effective communication.

Keyword

NONMEM; Berkeley Madonna; R; Pharmacometrics; Simulation

MeSH Terms

Computer Simulation
Software

Figure

• 

  Figure 1 The structural model used in the example.

Reference

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