Imaging Sci Dent.  2017 Sep;47(3):209-213. 10.5624/isd.2017.47.3.209.

Central giant cell lesion of the mandible in a 2-year old girl

• Oda T
• Sue M
• Okada Y
• Kanri Y
• Ono J
• Ogura I

• KMID: 2390086
• DOI: http://doi.org/10.5624/isd.2017.47.3.209

Abstract

Central giant cell lesions are rare, benign, osteolytic, pseudocystic, solitary, localized lesions that are common in the skeletal structure, but less so in the maxillofacial region. Furthermore, to perform panoramic radiography and cone-beam computed tomography, it is necessary to prepare patients properly and to position their heads carefully. However, this can be difficult in pediatric patients, who may be anxious. In this report, we describe the case of a central giant cell lesion of the mandible in a 2-year-old girl that was evaluated with multidetector computed tomography.

Keyword

Granuloma, Giant Cell; Multidetector Computed Tomography; Mandible; Child

MeSH Terms

Child
Child, Preschool
Cone-Beam Computed Tomography
Female*
Giant Cells*
Granuloma, Giant Cell
Head
Humans
Mandible*
Multidetector Computed Tomography
Radiography, Panoramic

Figure

• 

  Fig. 1 A clinical intraoral photograph shows an extracted tooth wound in the central area.

• 

  Fig. 2 A periapical radiograph shows root resorption of the left mandibular lateral deciduous incisor of the mandible.

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  Fig. 3 Axial soft-tissue algorithm CT images (A and B) show a mass lesion along the central area (arrow). Bone-tissue algorithm CT images (C and D) show an expansile lesion with an irregular and fairly well-defined area in the central area (arrow). CT, computed tomography.

• 

  Fig. 4 Multiplanar panoramic (A) and cross-sectional (B-D) reformation images more clearly demonstrate the root resorption of the left mandibular lateral deciduous incisor of the mandible and an expansile lesion in the central area (arrow).

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  Fig. 5 A and B. The multinucleated osteoclast-like giant cells are embedded in a fibrous stroma comprising oval to spindle-shaped cells around the region of hemorrhage. C. Positive immunohistochemical staining for CD68.

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