J Korean Ophthalmol Soc.  2017 Sep;58(9):1017-1022. 10.3341/jkos.2017.58.9.1017.

Analysis of Microorganisms and Antibiotics Susceptibility in Dacryocystitis

• Lee CH
• Lee TE
• You IC
• Cho NC
• Ahn M

• KMID: 2390063
• DOI: http://doi.org/10.3341/jkos.2017.58.9.1017

Abstract

PURPOSE
This article analyzes the microorganisms and antibiotics susceptibility in dacryocystitis.
METHODS
In this study, patients who were diagnosed with acute and chronic dacryocystitis with nasolacrimal duct obstruction were selected and underwent endoscopic endonasal dacryocystorhinostomy. Cultures were obtained from the lacrimal sac during operation from January 2008 to January 2016, and were used to analyze the microorganisms and antibiotics susceptibility.
RESULTS
The 67 patients, 9 were diagnosed with acute dacryocystitis and 58 were diagnosed with chronic dacryocystitis. Among them, 64 cases showed bacterial growth (95.5%). The most frequently detected bacteria was Staphylococcus epidermidis (S. epidermidis) (33.8%), followed by Staphylococcus aureus (S. aureus) (25.4%) and Enterobacter aerogenes (18.3%). S. epidermidis had the most powerful resistance to ciprofloxacin compared to the other bacteria (58.3%, p = 0.02). Except for S. epidermidis and S. aureus, the other bacteria responded to ciprofloxacin and gentamycin.
CONCLUSIONS
As a causative microorganism of dacryocystitis, S. epidermidis is becoming more prominent, and it is thought that S. epidermidis may be resistant to quinolones (i.e., broad-spectrum antibiotics). This resistance might be increasing the percentage of present S. epidermidis when viewed as a causal pathogen in dacryocystitis.

Keyword

Antibiotics susceptibility; Dacryocystitis; Microorganism

MeSH Terms

Anti-Bacterial Agents*
Bacteria
Ciprofloxacin
Dacryocystitis*
Dacryocystorhinostomy
Enterobacter aerogenes
Gentamicins
Humans
Nasolacrimal Duct
Quinolones
Staphylococcus aureus
Staphylococcus epidermidis
Anti-Bacterial Agents
Ciprofloxacin
Gentamicins
Quinolones

Figure

• 

  Figure 1 Ciprofloxacin resistance difference between S.epidermidis and other bacteria: resistance differance between S.epidermidis and S.aureus is statistically significant. Between S.aureus and gram negative species, it has no resistance differance. *By Chi-square test. S. epidermidis = Staphylococcus epidermis; S.aureus = Staphylococcus aureus.

• 

  Figure 2 Microorganism culture rate from 2008 to 2015. Before 2012 among the cultured bacteria, the proportion of S.epidermidis was small. But after 2012, proportion of the S.epidermidis has incresed significantly. S. epidermidis = Staphylococcus epidermis.

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