J Gastric Cancer.
2017 Sep;17(3):255-266. 10.5230/jgc.2017.17.e32.
A Novel Roux-en-Y Reconstruction Involving the Use of Two Circular Staplers after Distal Subtotal Gastrectomy for Gastric Cancer
- Affiliations
-
- 1Division of Gastrointestinal Surgery, Department of Surgery, Ajou University School of Medicine, Suwon, Korea. hansu@ajou.ac.kr
- 2Dr Ahn's Surgery Clinic, Yongin, Korea.
- 3Department of Surgery, Dongsuwon Hospital, Suwon, Korea.
- 4Department of Pathology, Ajou University School of Medicine, Suwon, Korea.
- KMID: 2389830
- DOI: http://doi.org/10.5230/jgc.2017.17.e32
Abstract
- PURPOSE
Although Roux-en-Y (R-Y) reconstruction after distal gastrectomy has several advantages, such as prevention of bile reflux into the remnant stomach, it is rarely used because of the technical difficulty. This prospective randomized clinical trial aimed to show the efficacy of a novel method of R-Y reconstruction involving the use of 2 circular staplers by comparing this novel method to Billroth-I (B-I) reconstruction.
MATERIALS AND METHODS
A total of 118 patients were randomly allocated into the R-Y (59 patients) and B-I reconstruction (59 patients) groups. R-Y anastomosis was performed using two circular staplers and no hand sewing. The primary end-point of this clinical trial was the reflux of bile into the remnant stomach evaluated using endoscopic and histological findings at 6 months after surgery.
RESULTS
No significant differences in clinicopathological findings were observed between the 2 groups. Although anastomosis time was significantly longer for the patients of the R-Y group (P<0.001), no difference was detected between the 2 groups in terms of the total surgery duration (P=0.112). Endoscopic findings showed a significant reduction of bile reflux in the remnant stomach in the R-Y group (P<0.001), and the histological findings showed that reflux gastritis was more significant in the B-I group than in the R-Y group (P=0.026).
CONCLUSIONS
The results of this randomized controlled clinical trial showed that compared with B-I reconstruction, R-Y reconstruction using circular staplers is a safe and feasible procedure. This clinical trial study was registered at www.ClinicalTrials.gov (registration No. NCT01142271).
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