Endocrinol Metab.  2017 Sep;32(3):370-374. 10.3803/EnM.2017.32.3.370.

Excessive Iodine Status among School-Age Children in Korea: A First Report

  • 1Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea. 79kyung@hanmail.net
  • 2Department Clinical Laboratory Science, Dong-Eui Institute of Technology, Busan, Korea.
  • 3Department of Biochemistry, Kosin University College of Medicine, Busan, Korea. jyjeong@kosin.ac.kr
  • 4Cancer Research Institute, Kosin University College of Medicine, Busan, Korea.


Korea is considered an iodine sufficient country, and several studies have been conducted regarding iodine status in healthy Korean adults, pregnant women, and preschool children. However, data on iodine status in Korean school-age children are lacking. Therefore, the iodine nutrition status of Korean school-age children was investigated by measuring urine iodine concentration (UIC).
This cross-sectional study conducted between April and September 2016 comprised 373 school-age children. UIC was determined using a modified microplate method employing ammonium persulfate digestion followed by Sandell-Kolthoff reaction.
The median UIC was 458.2 µg/L. Excessive iodine intake (>300 µg/L) was found in 286 children (76.7%), with extremely high values exceeding 1,000 µg/L in 19.6% of subjects. Insufficient iodine intake (<100 µg/L) was observed in eight children (2.1%). UIC values were not significantly different between sexes.
Korean school-age children showed excessive iodine intake. Therefore, education regarding adequate iodine intake in school-age children is needed.


Urine; Iodine; Schools; Korea
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