Ann Rehabil Med.  2017 Apr;41(2):279-289. 10.5535/arm.2017.41.2.279.

Predictors for Depressive Mood in Geriatric Patients After Traumatic Brain Injury: A Retrospective Cross-Sectional Study

• Kim JK
• Kim NY
• Kim YW

• KMID: 2389487
• DOI: http://doi.org/10.5535/arm.2017.41.2.279

Abstract

OBJECTIVE
To identify predictors for depressive mood in geriatric patients after traumatic brain injury (TBI).
METHODS
A retrospective review of patients' medical charts was performed in TBI patients who were older than 60 years and referred to the Department of Rehabilitation Medicine at Severance Hospital in 2002-2016. The patients were classified into two groups based on the Geriatric Depression Scale (GDS): non-depressive group (0≤GDS≤16) and depressive group (17≤GDS≤30). Data was collected on demographic, socioeconomic, comorbidities, and trauma-related factors, as well as the pathophysiology of TBI, localization of lesion, post-traumatic complications, functional level, and cognitive and linguistic function. Significant variables from univariate analysis were analyzed using logistic regression.
RESULTS
Forty-two patients were included, of whom 64.3% displayed a depressive mood. Patients in the depressive group had higher comorbidity scores (p=0.03), lower Functional Independence Measure (FIM) totals (p=0.03) and FIM motor (p=0.03) scores, higher modified Rankin Scale scores (p=0.04), and frequently had a bilateral or left side brain lesion (p=0.002). Higher comorbidity scores (odds ratio [OR], 1.764; 95% confidence interval [CI], 1.047-2.971), bilateral lesions (OR, 13.078; 95% CI, 1.786-95.780), and left side lesions (OR, 46.074; 95% CI, 3.175-668.502) were independently associated with a depressive mood in the multiple logistic regression analysis.
CONCLUSION
The risk of depressive mood in geriatric patients after TBI is associated with comorbidity, functional limitation, and the horizontal distribution of brain lesions. The most significant determining factors were comorbidity and the horizontal distribution of brain lesions. Early detection of risk factors is important to prevent and manage depressive mood in geriatric patients after TBI.

Keyword

Depression; Geriatric; Brain injuries; Risk factors

MeSH Terms

Brain
Brain Injuries*
Comorbidity
Cross-Sectional Studies*
Depression
Humans
Linguistics
Logistic Models
Rehabilitation
Retrospective Studies*
Risk Factors

Figure

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  Fig. 1 Flowchart of the subjects. A total of 126 geriatric patients with traumatic brain injury were assessed from January 1, 2002 to April 30, 2016. Finally, 42 patients were included and classified into two groups based on the Geriatric Depression Scale (GDS). K-MMSE, Korean version of Mini-Mental Status Examination.

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