J Korean Ophthalmol Soc.
2017 Jul;58(7):875-878. 10.3341/jkos.2017.58.7.875.
Full-thickness Macular Hole after Intravitreal Aflibercept Injection in a Patient with Wet Age-related Macular Degeneration
- Affiliations
-
- 1Department of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea. jazzhanul@hanmail.net
- KMID: 2387165
- DOI: http://doi.org/10.3341/jkos.2017.58.7.875
Abstract
- PURPOSE
To report a case of full-thickness macular hole following intravitreal aflibercept injection in a patient with wet age-related macular degeneration (AMD).
CASE SUMMARY
A 70-year-old man presented to our department with gradually decreasing vision in his left eye. Best-corrected visual acuity was measured as 0.8 in the right eye and 0.2 in the left eye. Fundus examination, fluorescein angiography, and optical coherence tomography (OCT) showed occult choroidal neovascularization associated with subretinal fluid in the left eye. The patient received several intravitreal ranibizumab and bevacizumab injections in his left eye but responded poorly to the treatment. The patient was switched to intravitreal aflibercept injection. After 1 month, the best corrected visual acuity in the left eye was decreased to 0.05. Although the fundus examination was indistinct, OCT confirmed the presence of a full-thickness macular hole. The patient underwent pars plana vitrectomy with internal limiting membrane peeling and fluid-gas exchange, 20% SF6 gas injection, phacoemulsification, and posterior chamber intraocular lens implantation. One month after the operation, the best corrected visual acuity was 0.2. The macular hole was closed completely, as confirmed by OCT.
CONCLUSIONS
Although the occurrence of a full-thickness macular hole after intravitreal aflibercept injection in the treatment of choroidal neovascularization with wet AMD is uncommon, physicians should pay attention for this complication.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Macular Hole after Single Intravitreal Injection of Ranibizumab in a Patient with Age-Related Macular Degeneration
- Macular Hole Following Intravitreal Ranibizumab Injections for Choroidal Neovascularization
- Short-term Effects of the Aflibercept Biosimilar Afilivu® on the Retinal Nerve Fiber Layer in Neovascular Age-related Macular Degeneration
- Rapid Progression of the Epiretinal Membrane after Intravitreal Aflibercept Injection
- Comparison of Choroidal Thickness Change between Ranibizumab and Aflibercept in Age-related Macular Degeneration: Six Month Results
