Psychiatry Investig.
2017 Jul;14(4):518-520. 10.4306/pi.2017.14.4.518.
Neosensitization to Multiple Drugs Following Valproate-Induced Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome
- Affiliations
-
- 1Department of Psychiatry, Jeju National University Hospital, Jeju, Republic of Korea.
- 2Department of Psychiatry, School of Medicine, Jeju National University, Jeju, Republic of Korea. handoll@jejunu.ac.kr
- 3Department of Dermatology, School of Medicine, Jeju National University, Jeju, Republic of Korea.
- KMID: 2387145
- DOI: http://doi.org/10.4306/pi.2017.14.4.518
Abstract
- Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is associated with severe skin eruptions, fever, hematological abnormalities, and multi-organ involvement. Although aromatic anticonvulsant drugs have been frequently associated with the manifestation of DRESS syndrome, its induction following treatment with nonaromatic anticonvulsants, such as valproate, has rarely been reported. Moreover, there are limited data regarding the development of neosensitization related to chemically unrelated drugs following an episode of DRESS syndrome. Here, a case of neosensitization to multiple drugs is described. The present case report describes a female patient who experienced neosensitization to amoxicillin, olanzapine, and quetiapine following the manifestation of DRESS syndrome induced by valproate.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- An Overview of Multiple Drug Hypersensitivity Syndrome
- Drug Reaction with Eosinophilia and Systemic Symptom Syndrome Due to Everolimus: A Case Report
- DRESS (drug reaction with eosinophilia and systemic symptoms) syndrome induced by lamotrigine in a child
- A Case of Sitagliptin Induced DRESS Syndrome
- Propylthiouracil Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) in Graves' Disease
