Soonchunhyang Med Sci.
2016 Dec;22(2):141-143. 10.0000/sms.2016.22.2.141.
Hypopituitarism Presenting as Osteoporotic Fracture after Cured Tuberculous Meningitis
- Affiliations
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- 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea. kaleey@hanmail.net
- KMID: 2387008
- DOI: http://doi.org/10.0000/sms.2016.22.2.141
Abstract
- Tuberculous meningitis is a well-known cause of hypothalamic pituitary dysfunction. However, deficiencies of anterior pituitary hormones may only become evident years after recovery because symptoms are of insidious-onset and nonspecific. Pituitary hormones are essential for normal growth and sexual development in childhood, and for maintenance of healthy body composition. In addition, pituitary hormones and vitamin D are important for cardiovascular and bone health. Although evidence of the relationship between hypovitaminosis D and hypopituitarism is limited, some studies suggested that the incidence of vitamin D deficiency increased in hypopituitarism. We describe herein an unusual case of hypopituitarism and severe hypovitaminosis D presenting as osteoporotic fracture after cured tuberculous meningitis.
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