J Korean Soc Clin Toxicol.  2017 Jun;15(1):51-55. 10.22537/jksct.2017.15.1.51.

A Fatal Case of Colchicine Poisoning

• Ko SH
• Lee GW

• KMID: 2386866
• DOI: http://doi.org/10.22537/jksct.2017.15.1.51

Abstract

Colchicine is a drug that has long been used to treat a variety of illnesses; however, it reportedly has adverse effects at apparent toxic doses as well as at lower and therapeutically recommended doses. The typical therapeutic dose of colchicine is up to 2.4 mg daily, although it is sometimes as high as 8-10 mg daily. Here, we describe a case in which the patient showed sudden deterioration and died because of unintentional colchicine poisoning with a relatively small dose. When a colchicine poisoned patient visits the hospital, the physician should identify the patient's colchicine poisoning dose and concomitant drugs. Moreover, the patients should be monitored intensively for 24 to 72 hours and managed with various supportive treatment methods early and actively.

Keyword

Colchicine; Poisoning; Sepsis; Cardiotoxicity

MeSH Terms

Cardiotoxicity
Colchicine*
Humans
Poisoning*
Sepsis
Colchicine