Res Vestib Sci.  2017 Jun;16(2):57-63. 10.21790/rvs.2017.16.2.57.

Four Cases of Wernicke's Encephalopathy with Impaired Horizontal Vestibular Ocular Reflexes

Affiliations
  • 1Department of Neurology, Chonbuk National University Hospital, Jeonju, Korea. ohsun@jbnu.ac.kr
  • 2Department of Neurology, Chonbuk National University Medical School, Jeonju, Korea.

Abstract

Wernicke's encephalopathy (WE) is a neurological disorder induced by a dietary vitamin B1 (thiamine) deficiency which is characterized by encephalopathy, gait ataxia, and variant ocular motor dysfunction. In addition to these classical signs of WE, a loss of the horizontal vestibulo-ocular reflex (VOR) is being reported as the major underdiagnosed symptoms in WE. In this retrospective single center study, we report four cases of WE initially presented with impaired horizontal VOR in addition to the classical clinical presentations, and imaging and neurotological laboratory findings were described.

Keyword

Wernicke's encephalopathy; Vestibulo-ocular reflex; Ataxia; Dizziness

MeSH Terms

Ataxia
Brain Diseases
Dizziness
Gait Ataxia
Nervous System Diseases
Reflex*
Reflex, Vestibulo-Ocular
Retrospective Studies
Thiamine
Wernicke Encephalopathy*
Thiamine
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