J Neurocrit Care.  2017 Jun;10(1):28-31. 10.18700/jnc.160100.

Ischemic Sciatic Neuropathy in a Patient with Liposarcoma

• Lee J
• Lee JH
• Kim GS
• Park MC
• Woo N
• Cho JH

• KMID: 2385883
• DOI: http://doi.org/10.18700/jnc.160100

Abstract

BACKGROUND
Various etiologies are the causative agents for sciatic neuropathy. We present here a case of ischemic sciatic neuropathy in a patient with liposarcoma.
CASE REPORT
A 55-year-old woman presented with severe pain and weakness of the left leg. She had a history of recurred retroperitoneal liposarcoma, and was being administered chemotherapy. Examination revealed weakness in ankle dorsiflexion, plantar flexion and hamstring. Complaints also included dysesthesia, and numbness in the sole and dorsum of the foot. Nerve conduction study showed low compound muscle action potentials and slow motor conduction velocity of left peroneal and tibial nerves, with indiscernible sensory nerve action potentials of the left superficial peroneal and sural nerves. Computed tomography angiography revealed occlusion of the left common iliac artery. Commencement of intravenous infusion of heparin resulted in skin color change and progression of the weakness. Hence, the patient underwent an emergency thrombectomy.
CONCLUSIONS
Ischemia should be considered as a cause of sciatic neuropathy in cancer patients, which requires management with timely treatment.

Keyword

Sciatic neuropathy; Liposarcoma; Ischemia

MeSH Terms

Action Potentials
Angiography
Ankle
Drug Therapy
Emergencies
Female
Foot
Heparin
Humans
Hypesthesia
Iliac Artery
Infusions, Intravenous
Ischemia
Leg
Liposarcoma*
Middle Aged
Neural Conduction
Paresthesia
Sciatic Neuropathy*
Skin Pigmentation
Sural Nerve
Thrombectomy
Tibial Nerve
Heparin

Figure

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  Figure 1. Findings in the lower extremity CT angiography. CT angiography showed long segmental occlusion of left common iliac, external iliac, femoral and popliteal artery. CT, computed tomography.

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