Ann Dermatol.  1999 Jan;11(1):41-46. 10.5021/ad.1999.11.1.41.

Two Cases of Generalized Pustular Psoriasis Followed by Acquired Bullous Disease

• Kim JW
• Kim SS
• Kim KJ
• Kim JM
• Lee CJ
• Shin HS

• KMID: 2383727
• DOI: http://doi.org/10.5021/ad.1999.11.1.41

Abstract

We herein present two cases of generalized pustular psoriasis(GPP) followed by acquired bullous diseases during antipsoriatic management. Although there were several reports de-scribing the coexistence of psoriasis vulgaris and autoimmune bullous diseases such as bullous pemphigoid or pemphigus vulgaris(PV), a coexistence of GPP and bullous disease was sparcely reported. In one patient, we could define atypical autoantigen which was distinct from the other known antigens in documented cases of bullous diseases. The other case was compatible with PV. The psoriatic lesions and bullous eruptions of the two patients cleared in several weeks after administration of cyclosporine.

Keyword

Generalized pustular psoriasis; Acquired bullous disease

MeSH Terms

Cyclosporine
Humans
Pemphigoid, Bullous
Pemphigus
Psoriasis*
Cyclosporine