Clin Endosc.  2017 Jan;50(1):81-86. 10.5946/ce.2016.027.

Laser Imaging Facilitates Early Detection of Synchronous Adenocarcinomas in Patients with Barrett's Esophagus

  • 1Division of Gastroenterology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Japan.
  • 2Department of Surgery, Jichi Medical University, Shimotsuke, Japan.


Barrett's adenocarcinoma may occur in multiple sites, and recurrence and metachronous lesions are the major problems with endoscopic resection. Therefore, early detection of such lesions is ideal to achieve complete resection and obtain improved survival rates with minimally invasive treatment. Laser imaging systems allow multiple modalities of endoscopic imaging by using white light laser, flexible spectral imaging color enhancement (FICE), blue laser imaging (BLI), and linked color imaging even at a distant view. However, the usefulness of these modalities has not been sufficiently reported regarding Barrett's adenocarcinoma. Here, we report on a patient with three synchronous lesions followed by one metachronous lesion in a long segment with changes of Barrett's esophagus, all diagnosed with this new laser endoscopic imaging system and enhanced by using FICE and/or BLI with high contrast compared with the surrounding mucosa. Laser endoscopic imaging may facilitate the detection of malignancies in patients with early Barrett's adenocarcinoma.


Barrett esophagus; Early synchronous neoplasms; Endoscopic submucosal dissection; Blue laser imaging; Flexible spectral image color enhancement

MeSH Terms

Barrett Esophagus*
Mucous Membrane
Survival Rate
Full Text Links
  • CE
export Copy
  • Twitter
  • Facebook
Similar articles
Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: