Korean J Helicobacter Up Gastrointest Res.  2012 Jun;12(2):55-61. 10.7704/kjhugr.2012.12.2.55.

Epidemiology of Barrett's Esophagus

Affiliations
  • 1Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea. mipark@ns.kosinmed.or.kr

Abstract

Barrett's esophagus was first described more than 50 years ago. Chronic gastroesophageal reflux disease can cause Barrett's esophagus, and predisposes the development of adenocarcinoma of the esophagus. Barrett's esophagus can be defined as the presence of specialized intestinal metaplasia within any length of the esophagus. However, there is still heterogeneity in definition of Barrett's esophagus, which has resulted in confusion and difficulties in comparing the various studies on the epidemiology of Barrett's esophagus. In Western countries, the incidence of Barrett's esophagus and esophageal adenocarcinoma has progressively increased. In contrast, the prevalence of Barrett's esophagus and esophageal adenocarcinoma is not increasing in Asia. Increased age, male sex, smoking, reflux symptoms and erosive esophagitis have been found to be risk factors for Barrett's esophagus in several studies from Asia. The prevalence of Barrett's esophagus in Asia outside Japan ranges from 0.06% to 6.2%, and is still lower than that in Western countries.

Keyword

Barrett's esophagus; Prevalence; Risk factors

MeSH Terms

Adenocarcinoma
Asia
Barrett Esophagus
Esophagitis
Esophagus
Gastroesophageal Reflux
Humans
Incidence
Japan
Male
Metaplasia
Population Characteristics
Prevalence
Risk Factors
Smoke
Smoking
Smoke
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