Korean J Med.  2017 Apr;92(2):209-212. 10.3904/kjm.2017.92.2.209.

Spontaneous Remission of Pernicious Anemia

• Sul H
• Moon WR
• Lee HJ
• Park SG
• Chung CH
• Park CY

• KMID: 2382665
• DOI: http://doi.org/10.3904/kjm.2017.92.2.209

Abstract

Pernicious anemia is a macrocytic anemia that is caused by vitamin B12 deficiency, itself a result of the absence of intrinsic factors due to autoimmune destruction of parietal cells. We report here the case of a 43-year-old female with spontaneous remission of pernicious anemia. The patient presented with fatigue. Her serum vitamin B12 level was low, hemoglobin level was 7.6 g/dL, and serologic tests for anti-intrinsic factor and anti-parietal cell antibodies were positive. We diagnosed her with pernicious anemia, but did not administer vitamin B12 because her hemoglobin level increased spontaneously. Since then, the patient's hemoglobin and serum vitamin B12 levels have been within the normal range.

Keyword

Anemia, Pernicious; Vitamin B12

MeSH Terms

Adult
Anemia, Macrocytic
Anemia, Pernicious*
Antibodies
Fatigue
Female
Humans
Intrinsic Factor
Rabeprazole
Reference Values
Remission, Spontaneous*
Serologic Tests
Vitamin B 12
Vitamin B 12 Deficiency
Antibodies
Intrinsic Factor
Vitamin B 12