Korean J Parasitol.  2015 Aug;53(4):379-383. 10.3347/kjp.2015.53.4.379.

Visceral Leishmaniasis in Rural Areas of Alborz Province of Iran and Implication to Health Policy

Affiliations
  • 1Department of Parasitology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
  • 2SDH Reseach Center, Alborz University of Medical Sciences, Karaj, Iran.
  • 3Center for Research of Endemic Parasites of Iran (CREPI), Tehran University of Medical Sciences, Tehran, Iran. mohebali@tums.ac.ir
  • 4Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Iran.
  • 5Department of Social Medicine, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
  • 6Center of Against Infectious Diseases, Health Depatment, Alborz University of Medical Sciences, Karaj, Iran.

Abstract

Visceral leishmaniasis (VL) or kala-azar mainly affects children in endemic areas. This study was conducted to determine the seroprevalence of VL using direct agglutination test (DAT) in children living in rural districts of Alborz Province located 30 km from Tehran capital city of Iran. Multi-stage cluster random sampling was applied. Blood samples were randomly collected from 1,007 children under 10 years of age in the clusters. A total of 37 (3.7%) of the studied population showed anti-Leishmania infantum antibodies with titers of > or =1:800. There was a significant association between positive sera and various parts of the rural areas of Alborz Province (P<0.002). Two children with anti-Leishmania infantum antibodies titers of > or =1:3,200 indicated kala-azar clinical features and treated with anti-leishmaniasis drugs in pediatric hospital. The findings of this study indicated that Leishmania infection is prevalent in rural areas of Alborz Province. Therefore, it is necessary to increase the awareness and alertness among physicians and public health managers, particularly in high-risk rural areas of the province in Iran.

Keyword

Leishmania infantum; visceral leishmaniasis; Kala-azar; human; Iran

MeSH Terms

Antibodies, Protozoan/blood
Child
Child, Preschool
Female
Health Policy
Humans
Iran/epidemiology
Leishmania infantum/immunology/isolation & purification/physiology
Leishmaniasis, Visceral/blood/*epidemiology/parasitology
Male
*Rural Health
Seroepidemiologic Studies
Antibodies, Protozoan
Full Text Links
  • KJP
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr