Epidemiol Health.  2016;38:e2016043. 10.4178/epih.e2016043.

Levels of adherence and factors associated with adherence to option B+ prevention of mother-to-child transmission among pregnant and lactating mothers in selected government health facilities of South Wollo Zone, Amhara Region, northeast Ethiopia, 2016

• Tsegaye D
• Deribe L
• Wodajo S

• KMID: 2380732
• DOI: http://doi.org/10.4178/epih.e2016043

Abstract

OBJECTIVES
The aim of this study was to measure the levels of adherence and to identify factors associated with adherence to option B+ prevention of mother-to-child transmission (PMTCT) among pregnant and lactating mothers in selected government health facilities of South Wollo Zone, Amhara Region, northeast Ethiopia.
METHODS
An institution-based cross-sectional quantitative study design was employed from March 1, 2016 to April 14, 2016, using a standard structured data collection instrument. A sample of 191 human immunodeficiency virus (HIV)-positive pregnant and lactating mothers who were receiving PMTCT follow-up in the selected health facilities participated in the study. The data were entered using EpiData 3.1 and analyzed using SPSS version 21. Bivariate and multivariate logistic regression analyses were employed to identify factors associated with adherence. The p-values <0.05 and 95% confidence intervals (CIs) were used to identify associations between independent predictors and the outcome variable.
RESULTS
The level of adherence to option B+ PMTCT drugs was 87.9%. Women who received in-hospital treatment, who lived in rural areas, and faced challenges in initiating lifelong option B+ treatment on the same-day that they were diagnosed with HIV were less likely to adhere to the treatment (adjusted odds ratios [95% CI] of 0.3 [0.11 to 0.82], 0.26 [0.1 to 0.73], and 0.08 [0.02 to 0.37], respectively).
CONCLUSIONS
Collaborative efforts of zonal health departments with health facility administrators and counselors are recommended for effective and efficient interventions focusing on hospitals, rural areas, and patients who face challenges on the day of their diagnosis.

Keyword

Medication adherence; Pregnant women; Breastfeeding; Ethiopia

MeSH Terms

Breast Feeding
Counseling
Data Collection
Diagnosis
Ethiopia*
Female
Fluconazole
Follow-Up Studies
Health Facilities*
Health Facility Administrators
HIV
Hospitals, Rural
Humans
Logistic Models
Medication Adherence
Mothers*
Odds Ratio
Pregnant Women
Fluconazole