Epidemiol Health.  2015;37:e2015047. 10.4178/epih/e2015047.

Modifiable risk factors of lung cancer in "never-smoker" women

Affiliations
  • 1Department of Preventive Medicine, Jeju National University School of Medicine, Jeju, Korea. jmbae@jejunu.ac.kr

Abstract

Korean women with a history of never smoking and with adenocarcinoma showed an increasing trend in lung cancer occurrence during 2002 to 2012. The two modifiable factors of never-smoker lung cancer in women are hormone and oncogenic virus infection. Based on previous studies, hormone replacement therapy (HRT) and human papillomavirus (HPV) infection might afford protection or be a risk factor, respectively. It is necessary to perform a pooled analysis of cohort studies to evaluate HRT and never-smoker lung cancer in women and a systematic review of case-control studies to determine the association between HPV infection and never-smoker lung cancer.

Keyword

Lung neoplasms; Risk factors; Hormone replacement therapy; Human papillomavirus; Meta-analysis

MeSH Terms

Adenocarcinoma
Case-Control Studies
Cohort Studies
Female
Hormone Replacement Therapy
Humans
Lung Neoplasms*
Lung*
Oncogenic Viruses
Risk Factors*
Smoke
Smoking
Smoke
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