Yeungnam Univ J Med.  1991 Jun;8(1):86-97. 10.12701/yujm.1991.8.1.86.

A clinical study of acute carbon monoxide intoxication

• Choi KC
• Park MY
• Hah JS
• Byun YJ
• Park CS

• KMID: 2377515
• DOI: http://doi.org/10.12701/yujm.1991.8.1.86

Abstract

To obtain the basic data of prognosis of acute carbon monoxide (CO) intoxication, one hundred and sixteen cases of CO intoxication defined by carboxyhemoglobin (COHb) and admitted via emergency room of Yeungnam University Hospital from Oct. '85 to April' 89 have been clinically analyzed and evaluated, including delayed postanoxic encephalopathy (DPE) and the following results were obtained. 1. The ratio of male to female was 1:1.5 and mental state was drowsy mostly (26.2% of 116 cases) 2. The more disturbed the mental state, the more decreased was the arterial pH and PaCOâ‚‚, which may be the result of metabolic acidosis. 3. The early laboratory findings in patients of CO intoxication were as follows: leukocytosis-65.5%, increase of hematocrit-23.3%, hyperglycemia-19.8%, increase of GPT-19.8% increase of creatinine-0.9% and glucosuria-12.1%. 4. The early findings of EKG were abnormal in 35.3%: change of rhythm-25.0%, abnormal ST segment 15.5% (change of rhythm and abnormal ST segment-5.2%) but the conduction disorder was not present. 5. The abnormal EEG above mild degree was 93.1%, of which moderate was most frequent (80.2%). 6. The incidence of DPE was 7.8% among all admitted CO patients. DPE cases had long duration of exposure time (8 hours), severe leukocytosis (20,000) and an abnormal EEG (MA).

Keyword

Acute carbon monoxide intoxication; Blood gas analysis; Delayed postanoxic encephalopathy

MeSH Terms

Acidosis
Blood Gas Analysis
Brain Diseases
Carbon Monoxide*
Carbon*
Carboxyhemoglobin
Clinical Study*
Electrocardiography
Electroencephalography
Emergency Service, Hospital
Female
Humans
Hydrogen-Ion Concentration
Incidence
Leukocytosis
Male
Prognosis
Carbon
Carbon Monoxide
Carboxyhemoglobin