J Lab Med Qual Assur.  2017 Mar;39(1):47-51. 10.15263/jlmqa.2017.39.1.47.

Performance Evaluation of ADVIA Centaur XPT

• Cho EJ
• Park KJ
• Lee W
• Chun S
• Min WK

• KMID: 2376752
• DOI: http://doi.org/10.15263/jlmqa.2017.39.1.47

Abstract

We have evaluated the performance of a recently developed immunoassay analyzer, ADVIA Centaur XPT (Siemens, Germany). Precision, linearity, and comparison studies were performed according to the CLSI guidelines. The test items evaluated were ferritin, folate, human epidermal growth factor receptor 2/neu, homocysteine, vitamin B₁₂, B-type natriuretic peptide, creatine kinase-myocardial band, myoglobin, procalcitonin, troponin I. Bio-Rad control materials, linearity materials, and patients' samples were used for the evaluation. For the correlation study, ADVIA Centaur XP (Siemens) were used as comparative methods. The total coefficients of variations (CVs) of the analytes were between 2.5% and 7.0%. The results of linearity evaluation were also acceptable for the range tested. Correlations with comparative methods were good. The overall analytical performance of ADVIA Centaur XPT is acceptable for the immunology analyzer. Therefore, ADVIA Centaur XPT is expected to be widely used.

Keyword

ADVIA Centaur XPT; Performance; Evaluation

MeSH Terms

Allergy and Immunology
Creatine
Ferritins
Folic Acid
Homocysteine
Humans
Immunoassay
Myoglobin
Natriuretic Peptide, Brain
Receptor, Epidermal Growth Factor
Statistics as Topic
Troponin I
Vitamins
Creatine
Ferritins
Folic Acid
Homocysteine
Myoglobin
Natriuretic Peptide, Brain
Receptor, Epidermal Growth Factor
Troponin I
Vitamins