Korean J Endocr Surg.  2009 Dec;9(4):211-213. 10.16956/kjes.2009.9.4.211.

Thyroid Carcinoma in Patients Less Than 20 Years of Age at Diagnosis: Clinicopathologic Characteristics

• Jung PY
• Han AR

• KMID: 2375735
• DOI: http://doi.org/10.16956/kjes.2009.9.4.211

Abstract

PURPOSE
This study determined the clinicopathologic characteristics in young patients with thyroid carcinoma.
METHODS
We retrospectively reviewed the records of 39 patients who were <20 years of age when diagnosed between January 1985 and December 2008.
RESULTS
The mean age was 17.28 years (range, 4~20 years). There were 33 females and 6 males, with a mean follow-up period of 110 months (range, 1~263 months). The initial surgery consisted of total thyroidectomy in 29 patients (74%), and lobectomy and isthmectomy in 10 patients (25%). The mean size of the tumors was 2.56 cm (range 0.4~7 cm), and 31 (79%) of 39 patients had perithyroidal tissue invasion. Papillary and follicular carcinoma was reported in 31 (79%) and 6 patients (15%), respectively. Three patients had a recurrence and no patients had progression of metastasis at the time of diagnosis.
CONCLUSION
Further collaborative studies are needed to refine the surgical approach, particularly the extent of lymph-node dissection, radioactive iodine dosing, and clinical approach.

Keyword

Thyroid carcinoma; Young patients; Clinicopathologic characteristics

MeSH Terms

Diagnosis*
Female
Follow-Up Studies
Humans
Iodine
Male
Neoplasm Metastasis
Recurrence
Retrospective Studies
Thyroid Gland*
Thyroid Neoplasms*
Thyroidectomy
Iodine

Reference

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