Korean J Endocr Surg.  2013 Jun;13(2):83-86. 10.0000/kjes.2013.13.2.83.

Thyroid Lobectomy for Treatment of Well Differentiated Thyroid Cancer Confined to One Lobe

• Kim YS
• Kim KC

• KMID: 2375419
• DOI: http://doi.org/10.0000/kjes.2013.13.2.83

Abstract

PURPOSE
There has been controversy of the lobectomy for well differentiated thyroid cancer (WDTC). Current guidelines recommend total thyroidectomy for the cancer over 1cm, despite previous report suggesting that the lobectomy provides similar excellent outcomes. The purpose of our study is to report our experience of WDTC treated by thyroid lobectomy.
METHODS
We retrospectively analyzed 284 patients with WDTC treated by thyroid lobectomy at department of Surgery in Chosun University Hospital from January 2002 to December 2010. Overall survival (OS) and disease-free survival (DFS) were determined by the Kaplan-Meier method. Factors predictive of recurrence by univariate and multivariate analysis were determined using the χ2 test and Cox proportional hazard model respectively.
RESULTS
With a mean follow-up of 60.4 months, OS and RFS for all patients were 97.9% and 96.5% respectively. No patient died due to WDTC. Univariate analysis showed statistically significant differences in recurrence by tumor size (P=0.013) and presence of invasion (P=0.039). However, Multivariate analysis showed no significant difference in local recurrence.
CONCLUSION
Patients with WDTC confined to one lobe can be safely treated by lobectomy.

Keyword

Thyroid cancer; Thyroid lobectomy; Local recurrence

MeSH Terms

Disease-Free Survival
Follow-Up Studies
Humans
Methods
Multivariate Analysis
Proportional Hazards Models
Recurrence
Retrospective Studies
Thyroid Gland*
Thyroid Neoplasms*
Thyroidectomy

Figure

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  Fig. 1. Overall survival (OS) and disease-free survival (DFS).

Reference

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