Ann Pediatr Endocrinol Metab.  2025 Feb;30(1):48-51. 10.6065/apem.2448296.148.

Pediatric thyroid cancer: key considerations based on the 2024 Korean Thyroid Association Differentiated Thyroid Cancer Management Guidelines

Affiliations
  • 1Department of Internal Medicine, Center for Thyroid Cancer, National Cancer Center, Goyang, Korea
  • 2Department of Pediatrics, Seoul National University Children’s Hospital, Seoul National University College of Medicine, Seoul, Korea


Figure

  • Fig. 1. Initial treatment and follow-up strategy based on the postoperative 3-tier Pediatric Risk Classification. TSH, thyroid-stimulating hormone; US, ultrasound; SPECT, single-photon emission computed tomography; CT, computed tomography; Tg, thyroglobulin.


Reference

References

1. Lee YA, Yun HR, Lee J, Moon H, Shin CH, Kim SG, et al. Trends in pediatric thyroid cancer incidence, treatment, and clinical course in Korea during 2004-2016: a nationwide population-based study. Thyroid. 2021; 31:902–11.
Article
2. Lee YA, Lee H, Im SW, Song YS, Oh DY, Kang HJ, et al. NTRK and RET fusion-directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake. J Clin Invest. 2021; 131:e144847.
3. Lee YA, Im SW, Jung KC, Chung EJ, Shin CH, Kim JI, et al. Predominant DICER1 pathogenic variants in pediatric follicular thyroid carcinomas. Thyroid. 2020; 30:1120–31.
Article
4. Moon JE, Oh SW, Kang HC, Koo BS, Kim K, Kim SW, et al. Korean Thyroid Association guidelines on the management of differentiated thyroid cancers; Part V. Pediatric differentiated thyroid cancer 2024. Int J Thyroidol. 2024; 17:193–207.
5. Lebbink CA, Links TP, Czarniecka A, Dias RP, Elisei R, Izatt L, et al. 2022 European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated thyroid carcinoma. Eur Thyroid J. 2022; 11:e220146.
Article
6. Francis GL, Waguespack SG, Bauer AJ, Angelos P, Benvenga S, Cerutti JM, et al. Management guidelines for children with thyroid nodules and differentiated thyroid cancer. Thyroid. 2015; 25:716–59.
Article
7. Sugino K, Nagahama M, Kitagawa W, Ohkuwa K, Uruno T, Matsuzu K, et al. Risk stratification of pediatric patients with differentiated thyroid cancer: is total thyroidectomy necessary for patients at any risk? Thyroid. 2020; 30:548–56.
Article
8. Nies M, Vassilopoulou-Sellin R, Bassett RL, Yedururi S, Zafereo ME, Cabanillas ME, et al. Distant metastases from childhood differentiated thyroid carcinoma: clinical course and mutational landscape. J Clin Endocrinol Metab. 2021; 106:e1683. –97.
Article
Full Text Links
  • APEM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2025 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr